Gene info
HGNC approved symbolCHD1L
HGNC IDHGNC:1916
HGNC approved namechromodomain helicase DNA binding protein 1-like
Entrez gene IDGeneID:9557
(SSTAR profile)
UniProt AC (human)Q86WJ1
UniProt ID (human)CHD1L_HUMAN
Pfam domainsHelicase_C PF00271 (381-459)
Pfam-B_2492 PB002492 (468-549)
SNF2_N PF00176 (49-328)
MGI symbolChd1l
MGI IDMGI:1915308
UniProt AC (mouse)Q9CXF7
UniProt ID (mouse)CHD1L_MOUSE
HGNC gene family tag#
HGNC gene family description#
FunctionChromatin remodeling
Modification#
PMID for information on functionPMID:19661379
Protein complex#
Target moleculeDNA
Target entity#
Product#
PMID for information on targetPMID:19661379
CommentA chromatin-remodeling enzyme, ALC1 (Amplified in Liver Cancer 1, also known as CHD1L), that interacts with poly(ADP-ribose) and catalyzes PARP1-stimulated nucleosome sliding.
Status of entry#

Expression statistics
Expression range: 0.0 to 191.17
Mean expression: 18.98 ± 12.53
Median expression: 16.55
Sample class Sample Expression (RLE-normalized CAGE tags per million)
Quantile over all genes
cell_line peripheral neuroectodermal tumor cell line:KU-SN.CNhs11830.10697-109G4 191.2 0.91
cell_line testicular germ cell embryonal carcinoma cell line:NEC14.CNhs12351.10591-108D6 90.1 0.801
cell_line neuroblastoma cell line:NB-1.CNhs11284.10539-107G8 86.6 0.823
cell_line colon carcinoma cell line:COLO-320.CNhs10737.10420-106C6 84.4 0.821
cell_line acute myeloid leukemia (FAB M5) cell line:THP-1 (fresh).CNhs10722.10399-106A3 65.4 0.779
cell_line testicular germ cell embryonal carcinoma cell line:NEC8.CNhs11726.10590-108D5 64.2 0.772
cell_line myelodysplastic syndrome cell line:SKM-1.CNhs11934.10772-110F7 62.5 0.776
cell_line hepatocellular carcinoma cell line: HepG2 ENCODE, biol_rep3.CNhs12330.10820-111C1 61.7 0.759
cell_line acute myeloid leukemia (FAB M2) cell line:Kasumi-1.CNhs13502.10788-110H5 60.7 0.782
cell_line acute myeloid leukemia (FAB M5) cell line:THP-1 (thawed).CNhs10724.10405-106A9 58.9 0.757
cell_line hepatocellular carcinoma cell line: HepG2 ENCODE, biol_rep1.CNhs12328.10818-111B8 58.7 0.758
cell_line acute myeloid leukemia (FAB M7) cell line:M-MOK.CNhs13049.10699-109G6 56.3 0.715
cell_line hepatocellular carcinoma cell line: HepG2 ENCODE, biol_rep2.CNhs12329.10819-111B9 55.7 0.754
cell_line chronic myeloblastic leukemia (CML) cell line:KCL-22.CNhs11886.10801-110I9 55.4 0.772
cell_line acute myeloid leukemia (FAB M5) cell line:THP-1 (revived).CNhs10723.10400-106A4 55.2 0.75
cell_line non-small cell lung cancer cell line:NCI-H1385.CNhs12193.10730-110B1 52.0 0.738
cell_line osteosarcoma cell line:143B/TK^(-)neo^(R).CNhs11279.10510-107D6 51.8 0.712
cell_line melanoma cell line:COLO 679.CNhs11281.10514-107E1 51.6 0.782
cell_line chronic myelogenous leukemia cell line:K562.CNhs11250.10454-106G4 51.4 0.724
cell_line acute myeloid leukemia (FAB M4) cell line:FKH-1.CNhs13503.10830-111D2 47.6 0.677
cell_line osteosarcoma cell line:HS-Os-1.CNhs11290.10558-107I9 47.1 0.728
cell_line acute lymphoblastic leukemia (B-ALL) cell line:BALL-1.CNhs11251.10455-106G5 44.8 0.689
cell_line acute myeloid leukemia (FAB M2) cell line:Kasumi-6.CNhs13052.10792-110H9 42.4 0.716
cell_line small cell lung carcinoma cell line:LK-2.CNhs11285.10541-107H1 42.4 0.658
cell_line astrocytoma cell line:TM-31.CNhs10742.10425-106D2 42.2 0.722
cell_line acute myeloid leukemia (FAB M2) cell line:NKM-1.CNhs11864.10765-110E9 42.0 0.686
cell_line teratocarcinoma cell line:NCR-G1.CNhs11884.10798-110I6 41.3 0.67
cell_line teratocarcinoma cell line:PA-1.CNhs11890.10807-111A6 41.1 0.688
cell_line retinoblastoma cell line:Y79.CNhs11267.10475-106I7 41.1 0.634
cell_line small cell lung carcinoma cell line:DMS 144.CNhs12808.10841-111E4 40.8 0.697
cell_line chronic myelogenous leukemia (CML) cell line:MEG-A2.CNhs11865.10766-110F1 40.6 0.681
cell_line acute myeloid leukemia (FAB M4eo) cell line:EoL-3.CNhs13057.10833-111D5 40.4 0.693
cell_line lymphoma, malignant, hairy B-cell cell line:MLMA.CNhs11935.10775-110G1 40.1 0.639
cell_line anaplastic squamous cell carcinoma cell line:RPMI 2650.CNhs11889.10805-111A4 39.5 0.612
cell_line signet ring carcinoma cell line:NUGC-4.CNhs11270.10483-107A6 38.6 0.7
cell_line teratocarcinoma cell line:NCC-IT-A3.CNhs11878.10790-110H7 38.2 0.659
cell_line chronic myelogenous leukemia cell line:K562 ENCODE, biol_rep3.CNhs12336.10826-111C7 37.3 0.64
cell_line acute myeloid leukemia (FAB M0) cell line:KG-1.CNhs13053.10827-111C8 37.1 0.648
cell_line acute myeloid leukemia (FAB M3) cell line:HL60.CNhs13055.10829-111D1 36.8 0.695
cell_line epithelioid sarcoma cell line:HS-ES-1.CNhs11247.10443-106F2 36.6 0.691
cell_line Burkitt's lymphoma cell line:RAJI.CNhs11268.10476-106I8 36.4 0.651
cell_line medulloblastoma cell line:D283 Med.CNhs12805.10838-111E1 36.1 0.583
cell_line testicular germ cell embryonal carcinoma cell line:ITO-II.CNhs11876.10786-110H3 36.1 0.655
cell_line acute myeloid leukemia (FAB M4) cell line:HNT-34.CNhs13504.10831-111D3 36.1 0.639
cell_line cord blood derived cell line:COBL-a untre