| HGNC approved symbol | CHD6 |
| HGNC ID | HGNC:19057 |
| HGNC approved name | chromodomain helicase DNA binding protein 6 |
| Entrez gene ID | GeneID:# (SSTAR profile) |
| UniProt AC (human) | Q8TD26 |
| UniProt ID (human) | CHD6_HUMAN |
| Pfam domains | BRK PF07533 (2400-2441) Chromo PF00385 (292-354, 375-429) Helicase_C PF00271 (817-897) Pfam-B_18962 PB018962 (1-49) Pfam-B_23619 PB023619 (1691-1909) Pfam-B_71010 PB071010 (1911-1953) Pfam-B_761 PB000761 (1271-1333, 1361-1519) SNF2_N PF00176 (464-751) |
| MGI symbol | Chd6 |
| MGI ID | MGI:1918639 |
| UniProt AC (mouse) | A3KFM7 |
| UniProt ID (mouse) | CHD6_MOUSE |
| HGNC gene family tag | # |
| HGNC gene family description | # |
| Function | Chromatin remodeling |
| Modification | # |
| PMID for information on function | PMID:12592387 |
| Protein complex | # |
| Target molecule | chromatin |
| Target entity | # |
| Product | # |
| PMID for information on target | PMID:12592387 |
| Comment | A novel gene encoding a protein with chromatin remodeling, helicase and DNA-binding motifs. This gene (CHD5=CHD6) is the fifth member of the CHD gene family identified in humans. |
| Status of entry | # |
| Expression range: | 1.04 to 182.92 |
| Mean expression: | 30.16 ± 22.13 |
| Median expression: | 24.67 |
| Sample class | Sample | Expression (RLE-normalized CAGE tags per million) | Quantile over all genes |
|---|---|---|---|
| cell_line | gastrointestinal carcinoma cell line:ECC12.CNhs11738.10615-108G3 | 182.9 | 0.901 |
| cell_line | breast carcinoma cell line:MCF7.CNhs11943.10482-107A5 | 121.9 | 0.867 |
| cell_line | small cell gastrointestinal carcinoma cell line:ECC10.CNhs11736.10610-108F7 | 111.4 | 0.854 |
| cell_line | small-cell gastrointestinal carcinoma cell line:ECC4.CNhs11734.10609-108F6 | 91.2 | 0.858 |
| cell_line | maxillary sinus tumor cell line:HSQ-89.CNhs10732.10414-106B9 | 90.9 | 0.847 |
| cell_line | Hodgkin's lymphoma cell line:HD-Mar2.CNhs11715.10435-106E3 | 83.9 | 0.798 |
| cell_line | neuroblastoma cell line:CHP-134.CNhs11276.10508-107D4 | 81.0 | 0.809 |
| cell_line | non T non B acute lymphoblastic leukemia (ALL) cell line:P30/OHK.CNhs10747.10430-106D7 | 78.8 | 0.771 |
| cell_line | neuroectodermal tumor cell line:FU-RPNT-1.CNhs11744.10637-108I7 | 76.3 | 0.804 |
| cell_line | ductal cell carcinoma cell line:KLM-1.CNhs11100.10438-106E6 | 69.7 | 0.814 |
| cell_line | gastric adenocarcinoma cell line:MKN1.CNhs11737.10614-108G2 | 69.5 | 0.833 |
| cell_line | testicular germ cell embryonal carcinoma cell line:NEC15.CNhs12362.10593-108D8 | 68.6 | 0.769 |
| cell_line | pleomorphic hepatocellular carcinoma cell line:SNU-387.CNhs11933.10706-109H4 | 67.9 | 0.812 |
| cell_line | acute lymphoblastic leukemia (T-ALL) cell line:HPB-ALL.CNhs10746.10429-106D6 | 65.5 | 0.753 |
| cell_line | breast carcinoma cell line:MDA-MB-453.CNhs10736.10419-106C5 | 64.0 | 0.772 |
| cell_line | merkel cell carcinoma cell line:MKL-1.CNhs12838.10843-111E6 | 61.4 | 0.748 |
| cell_line | hepatoblastoma cell line:HuH-6.CNhs11742.10633-108I3 | 60.6 | 0.717 |
| cell_line | anaplastic carcinoma cell line:8305C.CNhs10745.10428-106D5 | 60.3 | 0.828 |
| cell_line | argyrophil small cell carcinoma cell line:TC-YIK.CNhs11725.10589-108D4 | 57.7 | 0.792 |
| cell_line | glioblastoma cell line:A172, tech_rep1.CNhs11185.10444-106F3 | 57.6 | 0.781 |
| cell_line | neuroblastoma cell line:NH-12.CNhs11811.10555-107I6 | 57.6 | 0.741 |
| cell_line | osteosarcoma cell line:143B/TK^(-)neo^(R).CNhs11279.10510-107D6 | 54.5 | 0.721 |
| cell_line | lung adenocarcinoma cell line:PC-14.CNhs10726.10408-106B3 | 53.6 | 0.735 |
| cell_line | cord blood derived cell line:COBL-a 24h infection(-C).CNhs11049.10452-106G2 | 50.7 | 0.684 |
| cell_line | small cell lung carcinoma cell line:WA-hT.CNhs11812.10562-108A4 | 50.3 | 0.716 |
| cell_line | acute myeloid leukemia (FAB M7) cell line:M-MOK.CNhs13049.10699-109G6 | 49.3 | 0.686 |
| cell_line | glioblastoma cell line:A172, tech_rep2.CNhs11248.10444-106F3 | 49.2 | 0.749 |
| cell_line | malignant trichilemmal cyst cell line:DJM-1.CNhs10730.10412-106B7 | 49.2 | 0.708 |
| cell_line | somatostatinoma cell line:QGP-1.CNhs11869.10781-110G7 | 49.0 | 0.763 |
| cell_line | serous cystadenocarcinoma cell line:HTOA.CNhs11827.10693-109F9 | 48.9 | 0.786 |
| cell_line | testicular germ cell embryonal carcinoma cell line:NEC14.CNhs12351.10591-108D6 | 48.6 | 0.681 |
| cell_line | clear cell carcinoma cell line:TEN.CNhs11930.10636-108I6 | 48.3 | 0.767 |
| cell_line | neuroectodermal tumor cell line:FU-RPNT-2.CNhs11753.10663-109C6 | 48.2 | 0.716 |
| cell_line | epidermoid carcinoma cell line:A431.CNhs10743.10426-106D3 | 47.7 | 0.726 |
| cell_line | splenic lymphoma with villous lymphocytes cell line:SLVL.CNhs10741.10424-106D1 | 47.7 | 0.711 |
| cell_line | retinoblastoma cell line:Y79.CNhs11267.10475-106I7 | 46.9 | 0.678 |
| cell_line | mesodermal tumor cell line:HIRS-BM.CNhs12191.10696-109G3 | 46.7 | 0.729 |
| cell_line | transitional-cell carcinoma cell line:5637.CNhs10735.10418-106C4 | 46.5 | 0.712 |
| cell_line | hepatocellular carcinoma cell line: HepG2 ENCODE, biol_rep3.CNhs12330.10820-111C1 | 46.2 | 0.708 |
| cell_line | testicular germ cell embryonal carcinoma cell line:NEC8.CNhs11726.10590-108D5 | 45.9 | 0.691 |
| cell_line | neuroblastoma cell line:NBsusSR.CNhs11818.10607-108F4 | 45.8 | 0.73 |
| cell_line | colon carcinoma cell line:CACO-2.CNhs11280.10513-107D9 | 45.7 | 0.726 |
| cell_line | medulloblastoma cell line:D283 Med.CNhs12805.10838-111E1 | 45.7 | 0.653 |
| cell_line | hairy cell leukemia cell line:Mo.CNhs11843.10712-109I1 | 45.5 | 0.717 |
| cell_line | choriocarcinoma cell line:BeWo.CNhs10740.10423-106C9 | 45.0 | 0.725 |
| cell_line | non-small cell lung cancer cell line:NCI-H1385.CNhs12193.10730-110B1 | 44.8 | 0.712 |
| cell_line | merkel cell carcinoma cell line:MS-1.CNhs12839.10844-111E7 | 43.6 | 0.674 |
| cell_line | large cell lung carcinoma cell line:IA-LM.CNhs11277.10509-107D5 | 43.5 | 0.716 |
| cell_line | small cell lung carcinoma cell line:NCI-H82.CNhs12809.10842-111E5 | 42.9 | 0.653 |
| cell_line | mesothelioma cell line:Mero-82.CNhs13069.10853-111F7 | 42.8 | 0.724 |
| cell_line | anaplastic squamous cell carcinoma cell line:RPMI 2650.CNhs11889.10805-111A4 | 42.4 | 0.645 |
| cell_line | hepatocellular carcinoma cell line: HepG2 ENCODE, biol_rep2.CNhs12329.10819-111B9 | 42.1 | 0.681 |
| cell_line | small cell cervical cancer cell line:HCSC-1.CNhs11885.10800-110I8 | 41.9 | 0.696 |
| cell_line | oral squamous cell carcinoma cell line:HSC-3.CNhs11717.10545-107H5 | 41.3 | 0.734 |
| cell_line | giant cell carcinoma cell line:Lu99B.CNhs10751.10433-106E1 | 40.6 | 0.717 |
| cell_line | oral squamous cell carcinoma cell line:Ca9-22.CNhs10752.10434-106E2 | 40.5 | 0.712 |
| cell_line | renal cell carcinoma cell line:OS-RC-2.CNhs10729.10411-106B6 | 40.2 | 0.729 |
| cell_line | sacrococcigeal teratoma cell line:HTST.CNhs11829.10695-109G2 | 40.1 | 0.719 |
| cell_line | endometrial carcinoma cell line:OMC-2.CNhs11266.10497-107C2 | 39.8 | 0.711 |
| cell_line | embryonic pancreas cell line:2C6.CNhs11814.10603-108E9 | 39.4 | 0.673 |
| cell_line | epidermoid carcinoma cell line:Ca Ski.CNhs10748.10431-106D8 | 39.3 | 0.67 |
| cell_line | gall bladder carcinoma cell line:TGBC14TKB.CNhs11256.10470-106I2 | 38.9 | 0.67 |
| cell_line | mesothelioma cell line:ACC-MESO-4.CNhs11264.10494-107B8 | 38.8 | 0.67 |
| cell_line | peripheral neuroectodermal tumor cell line:KU-SN.CNhs11830.10697-109G4 | 38.7 | 0.66 |
| cell_line | synovial sarcoma cell line:HS-SY-II.CNhs11244.10441-106E9 | 37.7 | 0.63 |
| cell_line | hepatocellular carcinoma cell line: HepG2 ENCODE, biol_rep1.CNhs12328.10818-111B8 | 37.3 | 0.653 |
| cell_line | colon carcinoma cell line:COLO-320.CNhs10737.10420-106C6 | 37.2 | 0.63 |
| cell_line | papillotubular adenocarcinoma cell line:TGBC18TKB.CNhs10734.10417-106C3 | 36.4 | 0.646 |
| cell_line | rectal cancer cell line:TT1TKB.CNhs11255.10469-106I1 | 35.9 | 0.631 |
| cell_line | rhabdomyosarcoma cell line:RMS-YM.CNhs11269.10477-106I9 | 35.8 | 0.563 |
| cell_line | acute myeloid leukemia (FAB M6) cell line:F-36E.CNhs13060.10836-111D8 | 35.7 | 0.587 |
| cell_line | gastric adenocarcinoma cell line:MKN45.CNhs11819.10612-108F9 | 35.6 | 0.682 |
| cell_line | carcinoid cell line:SK-PN-DW.CNhs11846.10719-109I8 | 35.6 | 0.67 |
| cell_line | diffuse large B-cell lymphoma cell line:CTB-1.CNhs11741.10631-108I1 | 35.2 | 0.617 |
| cell_line | carcinosarcoma cell line:JHUCS-1.CNhs11747.10642-109A3 | 34.9 | 0.617 |
| cell_line | glioblastoma cell line:T98G.CNhs11272.10485-107A8 | 34.9 | 0.653 |
| cell_line | lens epithelial cell line:SRA 01/04.CNhs11750.10647-109A8 | 34.7 | 0.636 |
| cell_line | small cell lung carcinoma cell line:LK-2.CNhs11285.10541-107H1 | 34.0 | 0.588 |
| cell_line | cervical cancer cell line:ME-180.CNhs11289.10553-107I4 | 33.9 | 0.643 |
| cell_line | acute myeloid leukemia (FAB M7) cell line:MKPL-1.CNhs11888.10802-111A1 | 33.8 | 0.578 |
| cell_line | extraskeletal myxoid chondrosarcoma cell line:H-EMC-SS.CNhs10728.10410-106B5 | 33.2 | 0.62 |
| cell_line | acute myeloid leukemia (FAB M2) cell line:NK |