Gene info
HGNC approved symbolCTBP1
HGNC IDHGNC:2494
HGNC approved nameC-terminal binding protein 1
Entrez gene IDGeneID:1487
(SSTAR profile)
UniProt AC (human)Q13363
UniProt ID (human)CTBP1_HUMAN
Pfam domains2-Hacid_dh PF00389 (30-352)
2-Hacid_dh_C PF02826 (133-317)
MGI symbolCtbp1
MGI IDMGI:1201685
UniProt AC (mouse)O88712
UniProt ID (mouse)CTBP1_MOUSE
HGNC gene family tag#
HGNC gene family description#
FunctionChromatin remodeling
Modification#
PMID for information on functionPMID:21102443
Protein complexLSD-CoREST
Target moleculechromatin
Target entity#
Product#
PMID for information on targetPMID:21102443
CommentCtBP is a homodimer or heterodimer of CtBP1 and CtBP2 that assembles with a diverse array of factors that regulate chromatin structure.
Status of entry#

Expression statistics
Expression range: 12.81 to 302.85
Mean expression: 71.32 ± 31.11
Median expression: 66.08
Sample class Sample Expression (RLE-normalized CAGE tags per million)
Quantile over all genes
cell_line neuroepithelioma cell line:SK-N-MC.CNhs11853.10728-110A8 165.4 0.877
cell_line lymphangiectasia cell line:DS-1.CNhs11852.10727-110A7 161.3 0.906
cell_line bronchioalveolar carcinoma cell line:NCI-H358.CNhs11840.10709-109H7 152.6 0.887
cell_line hepatoblastoma cell line:HuH-6.CNhs11742.10633-108I3 127.0 0.843
cell_line acute myeloid leukemia (FAB M4eo) cell line:EoL-3.CNhs13057.10833-111D5 126.7 0.866
cell_line embryonic pancreas cell line:1B2C6.CNhs11731.10604-108F1 125.0 0.883
cell_line adenocarcinoma cell line:IM95m.CNhs11882.10796-110I4 122.6 0.892
cell_line tridermal teratoma cell line:HGRT.CNhs11828.10694-109G1 121.6 0.878
cell_line acute myeloid leukemia (FAB M6) cell line:F-36E.CNhs13060.10836-111D8 119.4 0.839
cell_line tubular adenocarcinoma cell line:SUIT-2.CNhs11883.10797-110I5 115.7 0.906
cell_line mucinous cystadenocarcinoma cell line:MCAS.CNhs11873.10784-110H1 112.6 0.871
cell_line diffuse large B-cell lymphoma cell line:CTB-1.CNhs11741.10631-108I1 107.8 0.842
cell_line NK T cell leukemia cell line:KHYG-1.CNhs11867.10777-110G3 103.7 0.85
cell_line leiomyoblastoma cell line:G-402.CNhs11848.10721-110A1 102.2 0.853
cell_line teratocarcinoma cell line:NCR-G1.CNhs11884.10798-110I6 102.0 0.845
cell_line embryonic pancreas cell line:1C3IKEI.CNhs11733.10606-108F3 101.1 0.876
cell_line embryonic pancreas cell line:2C6.CNhs11814.10603-108E9 100.4 0.861
cell_line anaplastic large cell lymphoma cell line:Ki-JK.CNhs11881.10795-110I3 99.0 0.847
cell_line acute myeloid leukemia (FAB M4eo) cell line:EoL-1.CNhs13056.10832-111D4 98.1 0.838
cell_line anaplastic squamous cell carcinoma cell line:RPMI 2650.CNhs11889.10805-111A4 98.0 0.835
cell_line neuroblastoma cell line:NBsusSR.CNhs11818.10607-108F4 97.3 0.858
cell_line sacrococcigeal teratoma cell line:HTST.CNhs11829.10695-109G2 96.2 0.881
cell_line acute myeloid leukemia (FAB M7) cell line:MKPL-1.CNhs11888.10802-111A1 95.9 0.817
cell_line biphenotypic B myelomonocytic leukemia cell line:MV-4-11.CNhs11845.10718-109I7 95.7 0.858
cell_line acute myeloid leukemia (FAB M1) cell line:HYT-1.CNhs13054.10828-111C9 95.5 0.858
cell_line chronic lymphocytic leukemia (T-CLL) cell line:SKW-3.CNhs11714.10416-106C2 94.0 0.831
cell_line pharyngeal carcinoma cell line:Detroit 562.CNhs11849.10723-110A3 93.4 0.882
cell_line embryonic pancreas cell line:1C3D3.CNhs11732.10605-108F2 93.3 0.885
cell_line adult T-cell leukemia cell line:ATN-1.CNhs10738.10421-106C7 93.3 0.853
cell_line myxofibrosarcoma cell line:MFH-ino.CNhs11729.10600-108E6 93.1 0.842
cell_line pancreatic carcinoma cell line:NOR-P1.CNhs11832.10698-109G5 93.0 0.849
cell_line somatostatinoma cell line:QGP-1.CNhs11869.10781-110G7 92.9 0.873
cell_line acute lymphoblastic leukemia (T-ALL) cell line:HPB-ALL.CNhs10746.10429-106D6 92.8 0.815
cell_line acute lymphoblastic leukemia (B-ALL) cell line:BALL-1.CNhs11251.10455-106G5 92.7 0.826
cell_line small cell lung carcinoma cell line:WA-hT.CNhs11812.10562-108A4 92.5 0.83
cell_line teratocarcinoma cell line:PA-1.CNhs11890.10807-111A6 90.0 0.839
cell_line normal embryonic palatal mesenchymal cell line:HEPM.CNhs11894.10813-111B3 89.9 0.888
cell_line neuroectodermal tumor cell line:FU-RPNT-2.CNhs11753.10663-109C6 89.7 0.842
cell_line myeloma cell line:PCM6.CNhs11258.10474-106I6 89.7 0.878
cell_line neurofibroma cell line:Hs 53.T.CNhs11854.10729-110A9 89.7 0.881
cell_line carcinoid cell line:SK-PN-DW.CNhs11846.10719-109I8 89.2 0.839
cell_line large cell lung carcinoma cell line:NCI-H460.CNhs12806.10839-111E2 88.7 0.878
cell_line Wilms' tumor cell line:HFWT.CNhs11728.10597-108E3 88.5 0.849
cell_line mesothelioma cell line:No36.CNhs13074.10857-111G2 88.1 0.853
cell_line mesothelioma cell line:Mero-83.CNhs13070.10854-111F8 87.6 0.853
cell_line acute lymphoblastic leukemia (B-ALL) cell line:NALM-6.CNhs11282.10534-107G3 87.6 0.807
cell_line hereditary spherocytic anemia cell line:WIL2-NS.CNhs11891.10808-111A7 86.4 0.823
cell_line medulloblastoma cell line:D283 Med.CNhs12805.10838-111E1 85.8 0.807
cell_line carcinosarcoma cell line:JHUCS-1.CNhs11747.10642-109A3 85.2 0.843
cell_line bronchogenic carcinoma cell line:ChaGo-K-1.CNhs11841.10710-109H8 84.9 0.826
cell_line merkel cell carcinoma cell line:MS-1.CNhs12839.10844-111E7 84.6 0.814
cell_line alveolar cell carcinoma cell line:SW 1573.CNhs11838.10708-109H6 84.1 0.831
cell_line medulloblastoma cell line:ONS-76.CNhs11861.10759-110E3 83.1 0.829
cell_line hepatic mesenchymal tumor cell line:LI90.CNhs11868.10778-110G4 82.5 0.9
cell_line small cell cervical cancer cell line:HCSC-1.CNhs11885.10800-110I8 82.3 0.819
cell_line prostate cancer cell line:DU145.CNhs11260.10490-107B4 82.3 0.844
cell_line Wilms' tumor cell line:G-401.CNhs11892.10809-111A8 82.3 0.838
cell_line gall bladder carcinoma cell line:TGBC14TKB.CNhs11256.10470-106I2 82.1 0.819
cell_line mucinous adenocarcinoma cell line:JHOM-1.CNhs11752.10648-109A9 82.1 0.852
cell_line acute myeloid leukemia (FAB M2) cell line:Kasumi-6.CNhs13052.10792-110H9 82.0 0.834
cell_line pagetoid sarcoma cell line:Hs 925.T.CNhs11856.10732-110B3 81.7 0.863
cell_line chronic myelogenous leukemia (CML) cell line:MEG-A2.CNhs11865.10766-110F1 79.8 0.823
cell_line acute lymphoblastic leukemia (T-ALL) cell line:Jurkat.CNhs11253.10464-106H5 79.7 0.811
cell_line acute myeloid leukemia (FAB M2) cell line:NKM-1.CNhs11864.10765-110E9 79.2 0.826
cell_line epithelioid sarcoma cell line:HS-ES-1.CNhs11247.10443-106F2 78.8 0.854
cell_line neuroblastoma cell line:NB-1.CNhs11284.10539-107G8 78.2 0.806
cell_line myxofibrosarcoma cell line:NMFH-1.CNhs11821.10684-109E9 78.1 0.847
cell_line liposarcoma cell line:SW 872.CNhs11851.10726-110A6 77.7 0.844
cell_line non-small cell lung cancer cell line:NCI-H1385.CNhs12193.10730-110B1 77.7 0.816
cell_line granulosa cell tumor cell line:KGN.CNhs11740.10624-108H3 77.4 0.848
cell_line choriocarcinoma cell line:SCH.CNhs11875.10785-110H2 77.1 0.837
cell_line chronic myeloblastic leukemia (CML) cell line:KCL-22.CNhs11886.10801-110I9 76.8 0.824
cell_line neuroblastoma cell line:NH-12.CNhs11811.10555-107I6 76.6 0.804
cell_line acute myeloid leukemia (FAB M4) cell line:FKH-1.CNhs13503.10830-111D2 75.2 0.786
cell_line neuroblastoma cell line:CHP-134.CNhs11276.10508-107D4 75.1 0.796
cell_line neuroectodermal tumor cell line:FU-RPNT-1.CNhs11744.10637-108I7 74.8 0.798
cell_line xeroderma pigentosum b cell line:XPL 17.CNhs11813.10563-108A5 74.7 0.834
cell_line mesothelioma cell line:Mero-82.CNhs13069.10853-111F7 73.9 0.83
cell_line rhabdomyosarcoma cell line:KYM-1.CNhs11877.10787-110H4 73.3 0.795
cell_line astrocytoma cell line:TM-31.CNhs10742.10425-106D2 73.3 0.831
cell_line acute myeloid leukemia (FAB M5) cell line:NOMO-1.CNhs13050.10764-110E8 73.2 0.81
cell_line mycosis fungoides, T cell lymphoma cell line:HuT 102 TIB-162.CNhs11858.10744-110C6 73.2 0.821
cell_line schwannoma cell line:HS-PSS, tech_rep2.CNhs11245.10442-106F1 72.7 0.849
cell_line merkel cell carcinoma cell line:MKL-1.CNhs12838.10843-111E6 72.6 0.776
cell_line acute myeloid leukemia (FAB M5) cell line:THP-1 (fresh).CNhs10722.10399-106A3 72.5 0.801
cell_line anaplastic carcinoma cell line:8305C.CNhs10745.10428-106D5 72.2 0.85
cell_line hepatocellular carcinoma cell line: HepG2 ENCODE, biol_rep2.CNhs12329.10819-111B9 71.9 0.804
cell_line gastric adenocarcinoma cell line:MKN1.CNhs11737.10614-108G2 71.9 0.843
cell_line lung adenocarcinoma cell line:PC-14.CNhs10726.10408-106B3 71.9 0.807
cell_line oral squamous cell carcinoma cell line:SAS.CNhs11810.10544-107H4 71.9 0.811
cell_line fibrosarcoma cell line:HT-1080.CNhs11860.10758-110E2 71.5 0.838
cell_line spindle cell sarcoma cell line:Hs 132.T.CNhs11857.10737-110B8 71.4 0.845
cell_line hepatocellular carcinoma cell line: HepG2 ENCODE, biol_rep1.CNhs12328.10818-111B8 70.9 0.796
cell_line neuroectodermal tumor cell line:TASK1.CNhs11866.10774-110F9 70.6 0.82
cell_line breast carcinoma cell line:MCF7.CNhs11943.10482-107A5 70.6 0.793
cell_line hairy cell leukemia cell line:Mo.CNhs11843.10712-109I1 69.9 0.802
cell_line adrenal cortex adenocarcinoma cell line:SW-13.CNhs11893.10810-111A9 69.8 0.806
cell_line keratoacanthoma cell line:HKA-1.CNhs11880.10791-110H8 69.4 0.828
cell_line B lymphoblastoid cell line: GM12878 ENCODE, biol_rep3.CNhs12333.10823-111C4 68.8 0.777
cell_line osteoclastoma cell line:Hs 706.T.CNhs11835.10704-109H2 68.6 0.844
cell_line serous adenocarcinoma cell line:JHOS-2.CNhs11746.10639-108I9 68.5 0.828
cell_line thyroid carcinoma cell line:TCO-1.CNhs11872.10783-110G9 68.4 0.815
cell_line rhabdomyosarcoma cell line:RMS-YM.CNhs11269.10477-106I9 68.3 0.741
cell_line mesodermal tumor cell line:HIRS-BM.CNhs12191.10696-109G3 68.1 0.816
cell_line retinoblastoma cell line:Y79.CNhs11267.10475-106I7 68.1 0.785
cell_line extraskeletal myxoid chondrosarcoma cell line:H-EMC-SS.CNhs10728.10410-106B5 68.0 0.823
cell_line acute myeloid leukemia (FAB M7) cell line:M-MOK.CNhs13049.10699-109G6 67.9 0.755
cell_line b cell line:RPMI1788.CNhs10744.10427-106D4 67.9 0.795
cell_line non T non B acute lymphoblastic leukemia (ALL) cell line:P30/OHK.CNhs10747.10430-106D7 67.9 0.722
cell_line acute myeloid leukemia (FAB M6) cell line:EEB.CNhs13059.10835-111D7 67.7 0.769
cell_line mesothelioma cell line:Mero-25.CNhs13066.10850-111F4 67.3 0.805
cell_line small cell lung carcinoma cell line:DMS 144.CNhs12808.10841-111E4 67.2 0.811
cell_line colon carcinoma cell line:COLO-320.CNhs10737.10420-106C6 67.1 0.781
cell_line B lymphoblastoid cell line: GM12878 ENCODE, biol_rep1.CNhs12331.10821-111C2 66.6 0.778
cell_line liposarcoma cell line:KMLS-1.CNhs11870.10782-110G8 66.3 0.849
cell_line Burkitt's lymphoma cell line:DAUDI.CNhs10739.10422-106C8 66.2 0.755
cell_line mesothelioma cell line:NCI-H2452.CNhs13064.10848-111F2 66.2 0.816
cell_line endometrial stromal sarcoma cell line:OMC-9.CNhs11249.10448-106F7 65.9 0.843
cell_line Hodgkin's lymphoma cell line:HD-Mar2.CNhs11715.10435-106E3 65.8 0.739
cell_line B lymphoblastoid cell line: GM12878 ENCODE, biol_rep2.CNhs12332.10822-111C3 65.8 0.771
cell_line plasma cell leukemia cell line:ARH-77.CNhs12807.10840-111E3 65.7 0.798
cell_line meningioma cell line:HKBMM.CNhs11945.10691-109F7 65.6 0.857
cell_line endometrial carcinoma cell line:OMC-2.CNhs11266.10497-107C2 65.5 0.82
cell_line glioblastoma cell line:A172, tech_rep2.CNhs11248.10444-106F3 65.2 0.815
cell_line mesenchymal stem cell line:Hu5/E18.CNhs11718.10568-108B1 65.2 0.804
cell_line small cell lung carcinoma cell line:LK-2.CNhs11285.10541-107H1 64.9 0.772
cell_line mesothelioma cell line:Mero-95.CNhs13073.10856-111G1 64.7 0.825
cell_line hepatocellular carcinoma cell line: HepG2 ENCODE, biol_rep3.CNhs12330.10820-111C1 64.6 0.773
cell_line acute myeloid leukemia (FAB M6) cell line:F-36P.CNhs13505.10837-111D9 64.4 0.767
cell_line mesothelioma cell line:ACC-MESO-1.CNhs11263.10493-107B7 63.9 0.838
cell_line serous adenocarcinoma cell line:SK-OV-3-R after co-culture with SOC-57-02-G, biol_rep1.CNhs13508.11843-124H7 63.9 0.85