Gene info
HGNC approved symbolDAXX
HGNC IDHGNC:2681
HGNC approved namedeath-domain associated protein
Entrez gene IDGeneID:1616
(SSTAR profile)
UniProt AC (human)Q9UER7
UniProt ID (human)DAXX_HUMAN
Pfam domainsDaxx PF03344 (1-740)
MGI symbolDaxx
MGI IDMGI:1197015
UniProt AC (mouse)O35613
UniProt ID (mouse)DAXX_MOUSE
HGNC gene family tag#
HGNC gene family description#
Function#
Modification#
PMID for information on functionPMID:23075851
Protein complex#
Target moleculehistone
Target entityH3.3
Product#
PMID for information on target#
CommentDAXX envelops a histone H3.3-H4 dimer for H3.3-specific recognition.
Status of entryNew

Expression statistics
Expression range: 1.29 to 81.09
Mean expression: 17.49 ± 8.56
Median expression: 16.14
Sample class Sample Expression (RLE-normalized CAGE tags per million)
Quantile over all genes
cell_line tridermal teratoma cell line:HGRT.CNhs11828.10694-109G1 81.1 0.819
cell_line cholangiocellular carcinoma cell line:HuH-28.CNhs11283.10536-107G5 56.7 0.831
cell_line embryonic kidney cell line: HEK293/SLAM infection, 24hr.CNhs11047.10451-106G1 55.9 0.717
cell_line acute myeloid leukemia (FAB M7) cell line:MKPL-1.CNhs11888.10802-111A1 53.6 0.697
cell_line anaplastic carcinoma cell line:8305C.CNhs10745.10428-106D5 37.8 0.712
cell_line leiomyoma cell line:10964C.CNhs11722.10569-108B2 36.4 0.793
cell_line embryonic pancreas cell line:2C6.CNhs11814.10603-108E9 34.6 0.648
cell_line Burkitt's lymphoma cell line:DAUDI.CNhs10739.10422-106C8 33.4 0.57
cell_line sacrococcigeal teratoma cell line:HTST.CNhs11829.10695-109G2 32.9 0.654
cell_line acute myeloid leukemia (FAB M0) cell line:KG-1.CNhs13053.10827-111C8 31.5 0.583
cell_line teratocarcinoma cell line:NCR-G1.CNhs11884.10798-110I6 30.3 0.584
cell_line thyroid carcinoma cell line:TCO-1.CNhs11872.10783-110G9 30.3 0.643
cell_line retinoblastoma cell line:Y79.CNhs11267.10475-106I7 30.0 0.527
cell_line leukemia, chronic megakaryoblastic cell line:MEG-01.CNhs11859.10752-110D5 29.5 0.598
cell_line chronic myelogenous leukemia (CML) cell line:MEG-A2.CNhs11865.10766-110F1 29.4 0.597
cell_line small cell cervical cancer cell line:HCSC-1.CNhs11885.10800-110I8 29.2 0.589
cell_line mesothelioma cell line:Mero-25.CNhs13066.10850-111F4 29.2 0.65
cell_line merkel cell carcinoma cell line:MKL-1.CNhs12838.10843-111E6 29.0 0.517
cell_line chronic lymphocytic leukemia (T-CLL) cell line:SKW-3.CNhs11714.10416-106C2 28.6 0.606
cell_line lymphoma, malignant, hairy B-cell cell line:MLMA.CNhs11935.10775-110G1 28.4 0.54
cell_line adrenal cortex adenocarcinoma cell line:SW-13.CNhs11893.10810-111A9 28.3 0.586
cell_line hepatocellular carcinoma cell line: HepG2 ENCODE, biol_rep1.CNhs12328.10818-111B8 28.1 0.563
cell_line diffuse large B-cell lymphoma cell line:CTB-1.CNhs11741.10631-108I1 28.1 0.553
cell_line hepatocellular carcinoma cell line: HepG2 ENCODE, biol_rep2.CNhs12329.10819-111B9 28.0 0.556
cell_line neuroblastoma cell line:NH-12.CNhs11811.10555-107I6 28.0 0.511
cell_line schwannoma cell line:HS-PSS, tech_rep2.CNhs11245.10442-106F1 27.9 0.619
cell_line hepatocellular carcinoma cell line: HepG2 ENCODE, biol_rep3.CNhs12330.10820-111C1 27.4 0.548
cell_line rhabdomyosarcoma cell line:RMS-YM.CNhs11269.10477-106I9 27.3 0.474
cell_line NK T cell leukemia cell line:KHYG-1.CNhs11867.10777-110G3 27.2 0.551
cell_line pagetoid sarcoma cell line:Hs 925.T.CNhs11856.10732-110B3 27.0 0.612
cell_line xeroderma pigentosum b cell line:XPL 17.CNhs11813.10563-108A5 26.9 0.593
cell_line large cell non-keratinizing squamous carcinoma cell line:SKG-II-SF.CNhs11825.10692-109F8 26.9 0.579
cell_line small cell gastrointestinal carcinoma cell line:ECC10.CNhs11736.10610-108F7 26.5 0.479
cell_line chronic myelogenous leukemia cell line:KU812.CNhs10727.10409-106B4 26.4 0.499
cell_line acute lymphoblastic leukemia (T-ALL) cell line:Jurkat.CNhs11253.10464-106H5 26.1 0.549
cell_line fibrosarcoma cell line:HT-1080.CNhs11860.10758-110E2 26.0 0.598
cell_line embryonic pancreas cell line:1B2C6.CNhs11731.10604-108F1 25.9 0.565
cell_line mesothelioma cell line:NCI-H226.CNhs13062.10846-111E9 25.9 0.608
cell_line acute myeloid leukemia (FAB M5) cell line:THP-1 (thawed).CNhs10724.10405-106A9 25.5 0.527
cell_line meningioma cell line:HKBMM.CNhs11945.10691-109F7 25.4 0.639
cell_line endometrial stromal sarcoma cell line:OMC-9.CNhs11249.10448-106F7 25.4 0.593
cell_line argyrophil small cell carcinoma cell line:TC-YIK.CNhs11725.10589-108D4 25.2 0.553
cell_line acute myeloid leukemia (FAB M5) cell line:THP-1 (revived).CNhs10723.10400-106A4 24.8 0.521
cell_line acute lymphoblastic leukemia (T-ALL) cell line:HPB-ALL.CNhs10746.10429-106D6 24.7 0.452
cell_line acute lymphoblastic leukemia (B-ALL) cell line:BALL-1.CNhs11251.10455-106G5 24.5 0.515
cell_line spindle cell sarcoma cell line:Hs 132.T.CNhs11857.10737-110B8 24.5 0.619
cell_line fibrous histiocy