Gene info
HGNC approved symbolANP32A
HGNC approved nameacidic (leucine-rich) nuclear phosphoprotein 32 family, member A
Entrez gene IDGeneID:8125
(SSTAR profile)
UniProt AC (human)P39687
UniProt ID (human)AN32A_HUMAN
Pfam domainsLRR_9 PF14580 (17-166)
MGI symbolAnp32a
MGI IDMGI:108447
UniProt AC (mouse)O35381
UniProt ID (mouse)AN32A_MOUSE
HGNC gene family tagANP32
HGNC gene family descriptionANP32 acidic nuclear phosphoproteins
FunctionChromatin remodeling cofactor
PMID for information on functionPMID:11163245
Protein complex#
Target moleculechromatin
Target entity#
PMID for information on targetPMID:11163245
Commentpp32 = ANP32A is a member of a family of leucine-rich acidic nuclear proteins ( 7 and 19). Results suggest potential roles of INHAT subunits in chromatin remodeling and transcriptional regulation; INHAT complex including pp32 inhibits the HAT activity of p300/CBP and PCAF by binding to their substrate, histones.
Status of entry#

Expression statistics
Expression range: 3.58 to 267.94
Mean expression: 55.29 ± 29.36
Median expression: 49.1
Sample class Sample Expression (RLE-normalized CAGE tags per million)
Quantile over all genes
cell_line lymphoma, malignant, hairy B-cell cell line:MLMA.CNhs11935.10775-110G1 267.9 0.909
cell_line bile duct carcinoma cell line:TFK-1.CNhs11265.10496-107C1 212.5 0.939
cell_line acute myeloid leukemia (FAB M5) cell line:U-937 DE-4.CNhs13058.10834-111D6 167.6 0.885
cell_line acute myeloid leukemia (FAB M3) cell line:HL60.CNhs13055.10829-111D1 165.3 0.887
cell_line hereditary spherocytic anemia cell line:WIL2-NS.CNhs11891.10808-111A7 161.4 0.883
cell_line adrenal cortex adenocarcinoma cell line:SW-13.CNhs11893.10810-111A9 160.6 0.892
cell_line B lymphoblastoid cell line: GM12878 ENCODE, biol_rep3.CNhs12333.10823-111C4 157.9 0.878
cell_line B lymphoblastoid cell line: GM12878 ENCODE, biol_rep2.CNhs12332.10822-111C3 154.1 0.876
cell_line acute lymphoblastic leukemia (T-ALL) cell line:HPB-ALL.CNhs10746.10429-106D6 153.9 0.877
cell_line teratocarcinoma cell line:NCC-IT-A3.CNhs11878.10790-110H7 151.9 0.877
cell_line acute myeloid leukemia (FAB M6) cell line:F-36E.CNhs13060.10836-111D8 148.9 0.863
cell_line B lymphoblastoid cell line: GM12878 ENCODE, biol_rep1.CNhs12331.10821-111C2 145.5 0.878
cell_line acute myeloid leukemia (FAB M7) cell line:MKPL-1.CNhs11888.10802-111A1 143.8 0.872
cell_line small cell lung carcinoma cell line:LK-2.CNhs11285.10541-107H1 139.7 0.881
cell_line small cell lung carcinoma cell line:DMS 144.CNhs12808.10841-111E4 137.9 0.885
cell_line retinoblastoma cell line:Y79.CNhs11267.10475-106I7 136.7 0.866
cell_line acute lymphoblastic leukemia (B-ALL) cell line:NALM-6.CNhs11282.10534-107G3 133.2 0.864
cell_line small cell lung carcinoma cell line:NCI-H82.CNhs12809.10842-111E5 126.2 0.856
cell_line embryonic pancreas cell line:1B2C6.CNhs11731.10604-108F1 125.6 0.885
cell_line chronic myelogenous leukemia cell line:KU812.CNhs10727.10409-106B4 124.8 0.853
cell_line non T non B acute lymphoblastic leukemia (ALL) cell line:P30/OHK.CNhs10747.10430-106D7 124.7 0.844
cell_line myelodysplastic syndrome cell line:SKM-1.CNhs11934.10772-110F7 124.2 0.862
cell_line breast carcinoma cell line:MDA-MB-453.CNhs10736.10419-106C5 123.4 0.888
cell_line myxofibrosarcoma cell line:MFH-ino.CNhs11729.10600-108E6 122.6 0.871
cell_line diffuse large B-cell lymphoma cell line:CTB-1.CNhs11741.10631-108I1 120.8 0.853
cell_line Burkitt's lymphoma cell line:DAUDI.CNhs10739.10422-106C8 119.7 0.849
cell_line chronic lymphocytic leukemia (T-CLL) cell line:SKW-3.CNhs11714.10416-106C2 118.5 0.852
cell_line prostate cancer cell line:DU145.CNhs11260.10490-107B4 118.4 0.876
cell_line splenic lymphoma with villous lymphocytes cell line:SLVL.CNhs10741.10424-106D1 117.3 0.868
cell_line acute lymphoblastic leukemia (T-ALL) cell line:Jurkat.CNhs11253.10464-106H5 116.7 0.857
cell_line acute lymphoblastic leukemia (B-ALL) cell line:BALL-1.CNhs11251.10455-106G5 116.3 0.849
cell_line epitheloid carcinoma cell line: HelaS3 ENCODE, biol_rep1.CNhs12325.10815-111B5 116.2 0.861
cell_line epitheloid carcinoma cell line: HelaS3 ENCODE, biol_rep3.CNhs12327.10817-111B7 113.7 0.859
cell_line acute myeloid leukemia (FAB M4) cell line:HNT-34.CNhs13504.10831-111D3 112.9 0.853
cell_line acute myeloid leukemia (FAB M4eo) cell line:EoL-3.CNhs13057.10833-111D5 112.2 0.857
cell_line Hodgkin's lymphoma cell line:HD-Mar2.CNhs11715.10435-106E3 112.1 0.844
cell_line acute myeloid leukemia (FAB M0) cell line:KG-1.CNhs13053.10827-111C8 111.4 0.843
cell_line b cell line:RPMI1788.CNhs10744.10427-106D4 111.3 0.861
cell_line acute myeloid leukemia (FAB M6) cell line:F-36P.CNhs13505.10837-111D9 110.1 0.861
cell_line rhabdomyosarcoma cell line:KYM-1.CNhs11877.10787-110H4 110.0 0.85
cell_line mucinous cystadenocarcinoma cell line:MCAS.CNhs11873.10784-110H1 109.7 0.868
cell_line gastric cancer cell line:AZ521.CNhs11286.10549-107H9 108.7 0.875
cell_line hepatoblastoma cell line:HuH-6.CNhs11742.10633-108I3 108.3 0.806
cell_line epitheloid carcinoma cell line: HelaS3 ENCODE, biol_rep2.CNhs12326.10816-1