| HGNC approved symbol | DR1 |
| HGNC ID | HGNC:3017 |
| HGNC approved name | down-regulator of transcription 1, TBP-binding (negative cofactor 2) |
| Entrez gene ID | GeneID:1810 (SSTAR profile) |
| UniProt AC (human) | Q01658 |
| UniProt ID (human) | NC2B_HUMAN |
| Pfam domains | CBFD_NFYB_HMF PF00808 (11-75) |
| MGI symbol | Dr1 |
| MGI ID | MGI:1100515 |
| UniProt AC (mouse) | Q91WV0 |
| UniProt ID (mouse) | NC2B_MOUSE |
| HGNC gene family tag | # |
| HGNC gene family description | # |
| Function | Histone chaperone |
| Modification | # |
| PMID for information on function | PMID:18838386 |
| Protein complex | ATAC |
| Target molecule | histone |
| Target entity | # |
| Product | # |
| PMID for information on target | PMID:18838386 |
| Comment | YEATS2-NC2beta=DR1 histone fold module that interacts with the TATA-binding protein (TBP) and negatively regulates transcription when recruited to a promoter. |
| Status of entry | # |
| Expression range: | 10.22 to 141.36 |
| Mean expression: | 50.14 ± 16.94 |
| Median expression: | 48.32 |
| Sample class | Sample | Expression (RLE-normalized CAGE tags per million) | Quantile over all genes |
|---|---|---|---|
| cell_line | leukemia, chronic megakaryoblastic cell line:MEG-01.CNhs11859.10752-110D5 | 141.4 | 0.89 |
| cell_line | acute lymphoblastic leukemia (T-ALL) cell line:HPB-ALL.CNhs10746.10429-106D6 | 128.5 | 0.859 |
| cell_line | oral squamous cell carcinoma cell line:Ca9-22.CNhs10752.10434-106E2 | 115.0 | 0.891 |
| cell_line | acute myeloid leukemia (FAB M5) cell line:THP-1 (thawed).CNhs10724.10405-106A9 | 99.1 | 0.854 |
| cell_line | acute myeloid leukemia (FAB M5) cell line:THP-1 (revived).CNhs10723.10400-106A4 | 97.1 | 0.853 |
| cell_line | Burkitt's lymphoma cell line:DAUDI.CNhs10739.10422-106C8 | 94.9 | 0.819 |
| cell_line | cord blood derived cell line:COBL-a 24h infection(-C).CNhs11049.10452-106G2 | 92.2 | 0.825 |
| cell_line | acute |