Gene info
HGNC approved symbolKMT2B
Status of entry#
HGNC ID15840
HGNC approved namelysine (K)-specific methyltransferase 2B
Entrez gene ID9757
UniProt AC (human)Q9UMN6
UniProt ID (human)KMT2B_HUMAN
Pfam domainsFYRC PF05965 2411-2494, FYRN PF05964 1732-1782, PHD PF00628 1251-1303 1337-1396, Pfam-B_25060 PB025060 1783-1849, Pfam-B_25524 PB025524 1168-1202, Pfam-B_26440 PB026440 701-839, Pfam-B_27348 PB027348 2191-2289, Pfam-B_3353 PB003353 1981-2079, Pfam-B_6332 PB006332 1401-1479, Pfam-B_85509 PB085509 345-387, SET PF00856 2586-2691, zf-CXXC PF02008 958-1005, zf-HC5HC2H PF13771 1608-1686
MGI symbolKmt2b
MGI ID109565
UniProt AC (mouse)O08550
UniProt ID (mouse)KMT2B_MOUSE
HGNC gene family tagKMT
HGNC gene family descriptionChromatin-modifying enzymes / K-methyltransferases
FunctionHistone modification write
ModificationHistone methylation
PMID for information on function17707229
Protein complexMenin-associated_HMT, MLL2/3, COMPASS-like MLL3,4
Target moleculehistone
Target entityH3K4
ProductH3K4me3
UniProt ID of targets#
PMID for information on target17707229
CommentMLL (=KMT2B)-containing complexes methylate histone H3 at lysine 4 (H3K4) and have been implicated in the regulation of transcription.

Expression statistics
Expression range: N/A
Mean expression: N/A
Median expression: N/A
Sample class Sample Expression (RLE-normalized CAGE tags per million)
Quantile over all genes