Gene info
HGNC approved symbolSAP25
Status of entry#
HGNC ID41908
HGNC approved nameSin3A-associated protein, 25kDa
Entrez gene ID100316904
UniProt AC (human)Q8TEE9
UniProt ID (human)SAP25_HUMAN
Pfam domainsSAP25 PF15476 1-199
MGI symbolSap25
MGI ID3802945
UniProt AC (mouse)Q1EHW4
UniProt ID (mouse)SAP25_MOUSE
HGNC gene family tag#
HGNC gene family description#
FunctionHistone modification erase cofactor
ModificationHistone acetylation
PMID for information on function16449650
Protein complex#
Target moleculehistone
Target entity#
Product#
UniProt ID of targets#
PMID for information on target16449650
CommentSAP25 binds to the PAH1 domain of mSin3A, associates with the mSin3A-HDAC complex in vivo, and represses transcription when tethered to DNA. SAP25 is required for mSin3A-mediated, but not N-CoR-mediated, repression.

Expression statistics
Expression range: N/A
Mean expression: N/A
Median expression: N/A
Sample class Sample Expression (RLE-normalized CAGE tags per million)
Quantile over all genes