| HGNC approved symbol | HGNC ID | HGNC approved name | Entrez gene ID | UniProt AC (human) | UniProt ID (human) | Pfam domains | MGI symbol | MGI ID | UniProt AC (mouse) | UniProt ID (mouse) | HGNC gene family tag | HGNC gene family description | Function | Modification | PMID for information on function | Protein complex | Target molecule | Target entity | Product | PMID for information on target | Comment | Status of entry |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
HSPA1A
(details) |
5232 | heat shock 70kDa protein 1A | 3303 | P08107 | HSP71_HUMAN | HSP70 PF00012 6-612 | Hspa1a | 96244 | Q61696 | HS71A_MOUSE | HSP70 | Heat shock proteins / HSP70 | Histone modification write cofactor, Histone modification write cofactor | Histone methylation, Histone acetylation | 22123078 | CHD8, MLL2/3, MLL4/WBP7 | histone | # | # | 22123078 | # | # |
|
HSPA1A
(details) |
5232 | heat shock protein family A (Hsp70) member 1B | 3303 | P0DMV8 | HS71A_HUMAN | PF00012 | Hspa1a | 96244 | Q61696 | HS71A_MOUSE | HSPA | Heat shock 70kDa proteins | Histone modification write cofactor | Histone acetylation, Histone methylation, Histone ubiquitination | 16809764, 2123078 | # | Protein | HDAC | # | 16809764, 2123078, 24613385 | Enhances STUB1-mediated SMAD3 ubiquitination and degradation and facilitates STUB1-mediated inhibition of TGF-beta signaling. | New |