Protein complex info
Complex group nameSWI/SNF
Complex namePBAF
Status of entryUpdated
Genes in complex(ACTL6A#4|ACTL6B#5), ACTB#3, (ARID1A#30|ARID1B#31), ARID2#32, SMARCA4#561, SMARCE1#571, SMARCC1#566, SMARCC2#567, SMARCD1#568, SMARCD2#569, SMARCD3#570?, SMARCB1#565, PBRM1#420
Alternative namesSWI/SNF-B
Proteins involvedSMARCA4/BRG1/BAF190A, SMARCB1/BAF47, ACTL6A/BAF53A or ACTL6B/BAF53B, SMARCE1/BAF57, SMARCD1/BAF60A, SMARCD2/BAF60B, perhaps SMARCD3/BAF60C, SMARCC1/BAF155, SMARCC2/BAF170, PB1/BAF180, ARID2/BAF200, ARID1A/BAF250A or ARID1B/BAF250B and actin
Uniprot IDs of involved proteins
(ACL6A_HUMAN|ACL6B_HUMAN), ACTB_HUMAN, (ARI1A_HUMAN|ARI1B_HUMAN), ARID2_HUMAN, SMCA4_HUMAN, SMCE1_HUMAN, SMRC1_HUMAN, SMRC2_HUMAN, SMRD1_HUMAN, SMRD2_HUMAN, SMRD3_HUMAN?, SNF5_HUMAN, PB1_HUMAN
PMID for reference on complex composition11078522, 11780067, 15985610
Functionchromatin remodeling complex
PMID for reference on function11780067
Target molecule typechromatin
Specific target#
Product#
Target UniProt ID#
PMID for reference on targets and products#
CommentInvolved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Acts as a negative regulator of cell proliferation.