Protein complex info
Complex group nameHAT
Complex namePol2 elongator
Status of entryUpdated
Genes in complexIKBKAP#274, ELP2#187, ELP3#188, ELP4#189, ELP5#190, ELP6#191
Alternative namesRNA polymerase II elongator complex
Proteins involvedELP1, ELP2, ELP3, ELP4, ELP5, ELP6
Uniprot IDs of involved proteins
ELP1_HUMAN, ELP2_HUMAN, ELP3_HUMAN, ELP4_HUMAN, ELP5_HUMAN, ELP6_HUMAN
PMID for reference on complex composition11714725, 11818576
Functionhistone acetylation complex
PMID for reference on function11714725
Target molecule typehistone
Specific targetH3, H4
ProductH3ac, H4ac
Target UniProt IDH31_HUMAN, H31T_HUMAN, H32_HUMAN, H33_HUMAN, H3C_HUMAN, H4_HUMAN
PMID for reference on targets and products11714725
CommentA histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. Original name "RNA polymerase II elongator complex".