Protein complex info
Complex group nameHAT
Complex nameNSL
Status of entry#
Genes in complexHCFC1#239, KANSL1#295, KANSL2#296, KANSL3#297, KAT8#304, MCRS1#351, PHF20#439, OGT#406, WDR5#687
Alternative names#
Proteins involvedMOF/KAT8, KANSL1, KANSL2, KANSL3, MCRS1, PHF20, OGT1/OGT, WDR5 and HCFC1
Uniprot IDs of involved proteins
HCFC1_HUMAN, KANL1_HUMAN, KANL2_HUMAN, KANL3_HUMAN, KAT8_HUMAN, MCRS1_HUMAN, PHF20_HUMAN, OGT1_HUMAN, WDR5_HUMAN
PMID for reference on complex composition20018852
Functionhistone acetylation complex
PMID for reference on function20018852
Target molecule typehistone
Specific targetH4K16
ProductH4K16ac
Target UniProt IDH4_HUMAN
PMID for reference on targets and products20018852
CommentIt is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription.