Protein complex info
Complex group nameHAT
Complex nameNSL
Genes in complexHCFC1#239, KANSL1#295, KANSL2#296, KANSL3#297, KAT8#304, MCRS1#351, PHF20#439, OGT#406, WDR5#687
Alternative names#
Proteins involvedMOF/KAT8, KANSL1, KANSL2, KANSL3, MCRS1, PHF20, OGT1/OGT, WDR5 and HCFC1
Uniprot IDs of involved proteins
HCFC1_HUMAN, KANL1_HUMAN, KANL2_HUMAN, KANL3_HUMAN, KAT8_HUMAN, MCRS1_HUMAN, PHF20_HUMAN, OGT1_HUMAN, WDR5_HUMAN
PMID for reference on complex compositionPMID:20018852
Functionhistone acetylation complex
PMID for reference on functionPMID:20018852
Target molecule typehistone
Specific targetH4K16
ProductH4K16ac
Target UniProt IDH4_HUMAN
PMID for reference on targets and productsPMID:20018852
CommentIt is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription.
Status of entry#