Protein complex info
Complex group nameHDAC
Complex nameNuRD
Status of entryUpdated
Genes in complexCHD3#124, CHD4#125, HDAC1#241, HDAC2#244, KDM1A#305, MBD2#344, MBD3#345, MTA1#372, MTA2#373, MTA3#374, (GATAD2A#229|GATAD2B#230), RBBP4#497, RBBP7#499
Alternative namesNRD, CHD3/CHD4
Proteins involvedHDAC1, HDAC2, RBBP4, RBBP7, MTA1, MTA2, MTA3, MBD2, MBD3, p66, CHD3 or CHD4, LSD1
Uniprot IDs of involved proteins
CHD3_HUMAN, CHD4_HUMAN, HDAC1_HUMAN, HDAC2_HUMAN, KDM1A_HUMAN, MBD2_HUMAN, MBD3_HUMAN, MTA1_HUMAN, MTA2_HUMAN, MTA3_HUMAN, (P66A_HUMAN|P66B_HUMAN), RBBP4_HUMAN, RBBP7_HUMAN
PMID for reference on complex composition19644445, 10589671, 17289569, 22108599
Functionhistone deacetylation complex, histone methylation complex, chromatin remodelling complex
PMID for reference on function10589671, 22108599
Target molecule typehistone
Specific targetH3
Product#
Target UniProt IDH31_HUMAN, H31T_HUMAN, H32_HUMAN, H33_HUMAN, H3C_HUMAN
PMID for reference on targets and products11850414
CommentThe nucleosome remodeling and histone deacetylation complex.