Protein complex info
Complex group nameHDAC
Complex nameNuRD
Genes in complexCHD3#124, CHD4#125, HDAC1#241, HDAC2#244, KDM1A#305, MBD2#344, MBD3#345, MTA1#372, MTA2#373, MTA3#374, (GATAD2A#229|GATAD2B#230), RBBP4#497, RBBP7#499
Alternative namesNRD, CHD3/CHD4
Proteins involvedHDAC1, HDAC2, RBBP4, RBBP7, MTA1, MTA2, MTA3, MBD2, MBD3, p66, CHD3 or CHD4, LSD1
Uniprot IDs of involved proteins
CHD3_HUMAN, CHD4_HUMAN, HDAC1_HUMAN, HDAC2_HUMAN, KDM1A_HUMAN, MBD2_HUMAN, MBD3_HUMAN, MTA1_HUMAN, MTA2_HUMAN, MTA3_HUMAN, (P66A_HUMAN|P66B_HUMAN), RBBP4_HUMAN, RBBP7_HUMAN
PMID for reference on complex compositionPMID:19644445, PMID:10589671, PMID:17289569, PMID:22108599
Functionhistone deacetylation complex, histone methylation complex, chromatin remodeling complex
PMID for reference on functionPMID:10589671, PMID:22108599
Target molecule typehistone
Specific targetH3
Product#
Target UniProt IDH31_HUMAN, H31T_HUMAN, H32_HUMAN, H33_HUMAN, H3C_HUMAN
PMID for reference on targets and productsPMID:11850414
CommentThe nucleosome remodeling and histone deacetylation complex.
Status of entryUpdated