Protein complex info
Complex group namePcG and PcG-like
Complex nameRING2-L3MBTL2
Status of entryNew
Genes in complexCBX3#95, E2F6#180, (HDAC1#241|HDAC2#244), L3MBTL2#331, MGA#356, PCGF6#425, (RING1#505|RNF2#509), (RYBP#520|YAF2#693), TFDP1#630, WDR5#687
Alternative namesPRC1.6
Proteins involvedRING2, RYBP/YAF2, L3MBTL2, E2F6, PCGF6, CBX3, HDAC1/HDAC2, Dp-1, WDR5, MGA
Uniprot IDs of involved proteins
CBX3_HUMAN, E2F6_HUMAN, (HDAC1_HUMAN|HDAC2_HUMAN), LMBL2_HUMAN, MGAP_HUMAN, PCGF6_HUMAN, (RING1_HUMAN|RING2_HUMAN), (RYBP_HUMAN|YAF2_HUMAN), TFDP1_HUMAN, WDR5_HUMAN
PMID for reference on complex composition22325352, 24217316
FunctionPolycomb like complex
PMID for reference on function22325352, 24217316
Target molecule typehistone
Specific targetH2AK119
ProductH2AK119ub1
Target UniProt IDH2A1_HUMAN, H2A1A_HUMAN, H2A1B_HUMAN, H2A1C_HUMAN, H2A1D_HUMAN, H2A1H_HUMAN, H2A1J_HUMAN, H2A2A_HUMAN, H2A2B_HUMAN, H2A2C_HUMAN, H2A3_HUMAN, H2AB1_HUMAN, H2AB2_HUMAN, H2AJ_HUMAN, H2AV_HUMAN, H2AW_HUMAN, H2AX_HUMAN, H2AY_HUMAN, H2AZ_HUMAN
PMID for reference on targets and products#
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