Protein complex info
Complex group nameMLL
Complex nameCOMPASS-like MLL1,2
Status of entryNew
Genes in complexASH2L#40, DPY30#176, HCFC1#239, KAT8#304, (KMT2A#325|KMT2D#328), MEN1#355, RBBP5#498, WDR5#687
Alternative names#
Proteins involvedMLL1 or MLL2, MOF, Menin, ASH2L, DRY30, HCF1, RBBP5, WDR5
Uniprot IDs of involved proteins
ASH2L_HUMAN, DPY30_HUMAN, HCFC1_HUMAN, KAT8_HUMAN, (KMT2A_HUMAN|KMT2D_HUMAN), MEN1_HUMAN, RBBP5_HUMAN, WDR5_HUMAN
PMID for reference on complex composition22108599
Functionhistone methylation complex, histone acetylation complex
PMID for reference on function22108599
Target molecule typehistone
Specific targetH4K16
ProductH4K16ac
Target UniProt IDH4_HUMAN
PMID for reference on targets and products22108599
CommentHox-family gene regulator; tumor supressor activity.