Protein complex info
Complex group nameDUB
Complex namePR-DUB
Status of entry#
Genes in complexASXL1#41, BAP1#60
Alternative names#
Proteins involvedBAP1 and ASXL1
Uniprot IDs of involved proteins
ASXL1_HUMAN, BAP1_HUMAN
PMID for reference on complex composition20436459
Functionhistone deubiquitination complex
PMID for reference on function20436459
Target molecule typehistone
Specific targetH2AK119
ProductH2AK119ub1
Target UniProt IDH2A1_HUMAN, H2A1A_HUMAN, H2A1B_HUMAN, H2A1C_HUMAN, H2A1D_HUMAN, H2A1H_HUMAN, H2A1J_HUMAN, H2A2A_HUMAN, H2A2B_HUMAN, H2A2C_HUMAN, H2A3_HUMAN, H2AB1_HUMAN, H2AB2_HUMAN, H2AJ_HUMAN, H2AV_HUMAN, H2AW_HUMAN, H2AX_HUMAN, H2AY_HUMAN, H2AZ_HUMAN
PMID for reference on targets and products20436459
CommentA complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-119' (H2AK119ub1).