Protein complex info
Complex group nameSWI/SNF
Complex namenBAF
Status of entryUpdated
Genes in complexACTL6B#5, ACTB#3, (ARID1A#30|ARID1B#31), DPF1#172, DPF3#174, SMARCA2#560, SMARCA4#561, SMARCE1#571, SMARCC1#566, SMARCC2#567, SMARCD1#568, SMARCD3#570, SMARCB1#565
Alternative namesneuron-specific chromatin remodeling complex
Proteins involvedARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170, DPF1/BAF45B, DPF3/BAF45C, ACTL6B/BAF53B and actin
Uniprot IDs of involved proteins
ACL6B_HUMAN, ACTB_HUMAN, (ARI1A_HUMAN|ARI1B_HUMAN), DPF1_HUMAN, DPF3_HUMAN, SMCA2_HUMAN, SMCA4_HUMAN, SMCE1_HUMAN, SMRC1_HUMAN, SMRC2_HUMAN, SMRD1_HUMAN, SMRD3_HUMAN, SNF5_HUMAN
PMID for reference on complex composition10078207, 11078522, 18765789, by similarity
Functionchromatin remodeling complex
PMID for reference on function11078522
Target molecule typechromatin
Specific target#
Product#
Target UniProt ID#
PMID for reference on targets and products#
CommentThe neuron-specific chromatin remodeling complex. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth. During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state.