HGNC approved symbol | PRDM9 |
HGNC ID | HGNC:13994 |
HGNC approved name | PR domain containing 9 |
Entrez gene ID | GeneID:56979 (SSTAR profile) |
UniProt AC (human) | Q9NQV7 |
UniProt ID (human) | PRDM9_HUMAN |
Pfam domains | KRAB PF01352 (27-65) SSXRD PF09514 (170-202) zf-C2H2 PF00096 (860-882) zf-H2C2_2 PF13465 (540-562, 566-590, 594-619, 622-647, 650-674, 678-702, 706-731, 734-758, 762-786, 790-815, 818-843, 846-871) |
MGI symbol | Prdm9 |
MGI ID | MGI:2384854 |
UniProt AC (mouse) | Q96EQ9 |
UniProt ID (mouse) | PRDM9_MOUSE |
HGNC gene family tag | ZKRAB, ZNF |
HGNC gene family description | Zinc fingers, C2H2-type |
Function | Histone modification write |
Modification | Histone methylation |
PMID for information on function | PMID:17916234 |
Protein complex | # |
Target molecule | histone |
Target entity | H3K4 |
Product | H3K4me3 |
PMID for information on target | PMID:17916234 |
Comment | Meisetz, the mouse ortholog of the long PRDM9 isoform, is able to activate the progression into meiosis through the trimethylation of the lysine 4 on histone H3. |
Status of entry | # |
Expression range: | N/A |
Mean expression: | N/A |
Median expression: | N/A |
Sample class | Sample | Expression (RLE-normalized CAGE tags per million) | Quantile over all genes |
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