| Complex group name | HAT |
| Complex name | HBO1 |
| Genes in complex | MEAF6#383, (ING4#305|ING5#306), (JADE1#312|JADE2#313|JADE3#314)+, KAT7#328 |
| Alternative names | # |
| Proteins involved | ING4 or ING5, KAT7/HBO1, MEAF6, and one of JADE1, JADE2 and JADE3 |
| Uniprot IDs of involved proteins | EAF6_HUMAN, (ING4_HUMAN|ING5_HUMAN), (JADE1_HUMAN|JADE2_HUMAN|JADE3_HUMAN)+, KAT7_HUMAN |
| PMID for reference on complex composition | PMID:16387653 |
| Function | histone acetylation complex |
| PMID for reference on function | PMID:10438470 |
| Target molecule type | histone |
| Specific target | H3, H4 |
| Product | H3ac, H4ac |
| Target UniProt ID | H31_HUMAN, H31T_HUMAN, H32_HUMAN, H33_HUMAN, H3C_HUMAN, H4_HUMAN |
| PMID for reference on targets and products | PMID:10438470 |
| Comment | Has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. |
| Status of entry | # |