Gene info
HGNC approved symbolARID1B
HGNC approved nameAT rich interactive domain 1B (SWI1-like)
Entrez gene IDGeneID:57492
(SSTAR profile)
UniProt AC (human)Q8NFD5
UniProt ID (human)ARI1B_HUMAN
Pfam domainsARID PF01388 (1050-1140)
DUF3518 PF12031 (1926-2182)
Pfam-B_60945 PB060945 (291-369)
Pfam-B_7257 PB007257 (371-449)
MGI symbolArid1b
MGI IDMGI:1926129
UniProt AC (mouse)#
UniProt ID (mouse)#
HGNC gene family tagARID
HGNC gene family description#
FunctionHistone modification write
ModificationHistone ubiquitination
PMID for information on functionPMID:20086098
Protein complexBAF, nBAF, npBAF, PBAF, SWI/SNF-like_EPAFa, SWI/SNF-like EPAFB, SWI/SNF BRM-BRG1
Target moleculehistone, DNA
Target entityH2BK120, DNA motif
PMID for information on targetPMID:20086098
CommentThe characteristic member of human SWI/SNF-A is BAF250/ARID1, of which there are two isoforms, BAF250a/ARID1a and BAF250b/ARID1b. The immunopurified BAF250b E3 ubiquitin ligase was found to target histone H2B at lysine 120 for monoubiquitination in vitro.
Status of entry#

Expression statistics
Expression range: 0.0 to 132.84
Mean expression: 23.87 ± 16.33
Median expression: 19.15
Sample class Sample Expression (RLE-normalized CAGE tags per million)
Quantile over all genes
cell_line acute myeloid leukemia (FAB M4) cell line:FKH-1.CNhs13503.10830-111D2 132.8 0.867
cell_line acute myeloid leukemia (FAB M6) cell line:F-36E.CNhs13060.10836-111D8 72.6 0.757
cell_line chronic myelogenous leukemia cell line:KU812.CNhs10727.10409-106