Gene info
HGNC approved symbolAURKB
HGNC approved nameaurora kinase B
Entrez gene IDGeneID:9212
(SSTAR profile)
UniProt AC (human)Q96GD4
UniProt ID (human)AURKB_HUMAN
Pfam domainsPfam-B_34716 PB034716 (1-46)
Pkinase PF00069 (77-327)
MGI symbolAurkb
MGI IDMGI:107168
UniProt AC (mouse)O70126
UniProt ID (mouse)AURKB_MOUSE
HGNC gene family tagPPP1R
HGNC gene family descriptionSerine/threonine phosphatases / Protein phosphatase 1, regulatory subunits
FunctionHistone modification write
ModificationHistone phosphorylation
PMID for information on functionPMID:11856369
Protein complex#
Target moleculehistone
Target entityH3S10, H3S28
PMID for information on targetPMID:11856369
CommentAurora-B=AURKB directly phosphorylated H3, not only at Ser10 but also at Ser28.
Status of entry#

Expression statistics
Expression range: 0.0 to 160.24
Mean expression: 19.54 ± 23.45
Median expression: 10.51
Sample class Sample Expression (RLE-normalized CAGE tags per million)
Quantile over all genes
cell_line embryonic kidney cell line: HEK293/SLAM infection, 24hr.CNhs11047.10451-106G1 160.2 0.886
cell_line acantholytic squamous carcinoma cell line:HCC1806.CNhs11844.10717-109I6 137.5 0.868
cell_line small cell lung carcinoma cell line:NCI-H82.CNhs12809.10842-111E5 134.5 0.862
cell_line non T non B acute lymphoblastic leukemia (ALL) cell line:P30/OHK.CNhs10747.10430-106D7 127.8 0.852
cell_line NK T cell leukemia cell line:KHYG-1.CNhs11867.10777-110G3 116.6 0.863
cell_line acute lymphoblastic leukemia (T-ALL) cell line:HPB-ALL.CNhs10746.10429-106D6 105.8 0.829
cell_line adult T-cell leukemia cell line:ATN-1.CNhs10738.10421-106C7 104.8 0.866
cell_line teratocarcinoma cell line:NCR-