HGNC approved symbol | PARP2 |
HGNC ID | HGNC:272 |
HGNC approved name | poly (ADP-ribose) polymerase 2 |
Entrez gene ID | GeneID:10038 (SSTAR profile) |
UniProt AC (human) | Q9UGN5 |
UniProt ID (human) | PARP2_HUMAN |
Pfam domains | WGR PF05406 (116-194) PARP_reg PF02877 (231-363) PARP PF00644 (376-577) |
MGI symbol | Parp2 |
MGI ID | MGI:1341112 |
UniProt AC (mouse) | O88554 |
UniProt ID (mouse) | PARP2_MOUSE |
HGNC gene family tag | PARP |
HGNC gene family description | Poly (ADP-ribose) polymerases |
Function | Chromatin remodeling cofactor |
Modification | # |
PMID for information on function | PMID:20092359 |
Protein complex | # |
Target molecule | # |
Target entity | # |
Product | # |
PMID for information on target | PMID:20092359 |
Comment | PARP activity is involved in processes such as chromatin remodeling. Component of a base excision repair (BER) complex, containing at least XRCC1, PARP1, POLB and LRIG3. Homo- and heterodimer with PARP1. |
Status of entry | # |
Expression range: | 0.0 to 67.34 |
Mean expression: | 18.14 ± 11.24 |
Median expression: | 15.14 |