HGNC approved symbol | CDK2 |
HGNC ID | HGNC:1771 |
HGNC approved name | cyclin-dependent kinase 2 |
Entrez gene ID | GeneID:1017 (SSTAR profile) |
UniProt AC (human) | P24941 |
UniProt ID (human) | CDK2_HUMAN |
Pfam domains | Pkinase PF00069 (4-286) |
MGI symbol | Cdk2 |
MGI ID | MGI:104772 |
UniProt AC (mouse) | P97377 |
UniProt ID (mouse) | CDK2_MOUSE |
HGNC gene family tag | CDK |
HGNC gene family description | Cyclin-dependent kinases |
Function | Histone modification write |
Modification | Histone phosphorylation |
PMID for information on function | PMID:15753125 |
Protein complex | # |
Target molecule | histone |
Target entity | H1S, H1T |
Product | H1Sph, H1Tph |
PMID for information on target | PMID:15753125 |
Comment | Cdk2 is one of the enzymes recruited to replication foci (by Cdc45 or other fork proteins), followed by H1 phosphorylation and chromatin unfolding. |
Status of entry | # |