HGNC approved symbol | CDK7 |
HGNC ID | HGNC:1778 |
HGNC approved name | cyclin-dependent kinase 7 |
Entrez gene ID | GeneID:1022 (SSTAR profile) |
UniProt AC (human) | P50613 |
UniProt ID (human) | CDK7_HUMAN |
Pfam domains | Pkinase PF00069 (12-295) |
MGI symbol | Cdk7 |
MGI ID | MGI:102956 |
UniProt AC (mouse) | Q03147 |
UniProt ID (mouse) | CDK7_MOUSE |
HGNC gene family tag | CDK, TFIIH |
HGNC gene family description | Cyclin-dependent kinases, General transcription factor IIH complex subunits |
Function | Histone modification write |
Modification | Histone phosphorylation |
PMID for information on function | PMID:10722743 |
Protein complex | # |
Target molecule | histone |
Target entity | H1 |
Product | # |
PMID for information on target | PMID:10722743 |
Comment | Cdk7, is able to phosphorylate histone H1, and the basal activity is increased 2-fold in the presence of recombinant human cyclin H (the activating partner of Cdk7). |
Status of entry | # |