Gene info
| HGNC approved symbol | IKZF1 |
| HGNC ID | HGNC:13176 |
| HGNC approved name | IKAROS family zinc finger 1 (Ikaros) |
| Entrez gene ID | GeneID:10320 (SSTAR profile) |
| UniProt AC (human) | Q13422 |
| UniProt ID (human) | IKZF1_HUMAN |
| Pfam domains | zf-C2H2 PF00096 (145-167, 173-195, 201-224) |
| MGI symbol | Ikzf1 |
| MGI ID | MGI:1342540 |
| UniProt AC (mouse) | Q03267 |
| UniProt ID (mouse) | IKZF1_MOUSE |
| HGNC gene family tag | ZNF, IKZF |
| HGNC gene family description | Zinc fingers, C2H2-type, IKAROS zinc fingers |
| Function | Chromatin remodeling, TF |
| Modification | # |
| PMID for information on function | PMID:19141594 |
| Protein complex | # |
| Target molecule | DNA |
| Target entity | DNA motif |
| HOCOMOCO TFBS model | |
| Product | # |
| PMID for information on target | PMID:19141594 |
| Comment | Ikaros=IKZF1 forms dimers and multimers efficiently, and it has been proposed that Ikaros induces heterochromatization or chromatin remodeling of mouse DNA, resulting in repression or activation of target genes. The results provide insight into possible structural and functional roles of pericentromeric regions in mouse and human chromosomes. |
| Status of entry | # |
Expression statistics
| Expression range: | 0.0 to 314.26 |
| Mean expression: | 24.66 ± 49.87 |
| Median expression: | 0.0 |