HGNC approved symbol | CENPC |
HGNC ID | HGNC:1854 |
HGNC approved name | centromere protein C |
Entrez gene ID | GeneID:1060 (SSTAR profile) |
UniProt AC (human) | Q03188 |
UniProt ID (human) | CENPC_HUMAN |
Pfam domains | CENP_C_N PF15622 (1-320) CENP-C_mid PF15620 (324-596) CENP-C_C PF11699 (857-940) |
MGI symbol | Cenpc1 |
MGI ID | MGI:99700 |
UniProt AC (mouse) | P49452 |
UniProt ID (mouse) | CENPC_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | DNA modification |
Modification | DNA methylation |
PMID for information on function | PMID:19482874 |
Protein complex | # |
Target molecule | DNA |
Target entity | C |
Product | 5mC |
PMID for information on target | PMID:19482874 |
Comment | CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the histone code in these regions. |
Status of entry | # |
Expression range: | 0.0 to 329.1 |
Mean expression: | 30.02 ± 35.62 |
Median expression: | 18.48 |