HGNC approved symbol | NEK6 |
HGNC ID | HGNC:7749 |
HGNC approved name | NIMA-related kinase 6 |
Entrez gene ID | GeneID:10783 (SSTAR profile) |
UniProt AC (human) | Q9HC98 |
UniProt ID (human) | NEK6_HUMAN |
Pfam domains | Pkinase PF00069 (45-296) |
MGI symbol | Nek6 |
MGI ID | MGI:1891638 |
UniProt AC (mouse) | Q9ES70 |
UniProt ID (mouse) | NEK6_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Histone modification write |
Modification | Histone phosphorylation |
PMID for information on function | PMID:12054534 |
Protein complex | # |
Target molecule | histone |
Target entity | H1, H3 |
Product | H1ph, H3ph |
PMID for information on target | PMID:12054534 |
Comment | Recombinant hNek6 protein produced in insect cells effectively phosphorylates histones H1 and H3, but not casein. Thus Nek6 is a mitotic histone kinase which regulates chromatin condensation in mammalian cells. |
Status of entry | # |