HGNC approved symbol | CHD4 |
HGNC ID | HGNC:1919 |
HGNC approved name | chromodomain helicase DNA binding protein 4 |
Entrez gene ID | GeneID:1108 (SSTAR profile) |
UniProt AC (human) | Q14839 |
UniProt ID (human) | CHD4_HUMAN |
Pfam domains | CHDNT PF08073 (165-217) PHD PF00628 (373-414, 452-493) Chromo PF00385 (621-673) SNF2-rel_dom PF00176 (728-1024) Helicase_C PF00271 (1052-1164) DUF1087 PF06465 (1291-1350) CHDII_SANT-like PF06461 (1379-1520) CHDCT2 PF08074 (1726-1872) |
MGI symbol | Chd4 |
MGI ID | MGI:1344380 |
UniProt AC (mouse) | Q6PDQ2 |
UniProt ID (mouse) | CHD4_MOUSE |
HGNC gene family tag | PHF |
HGNC gene family description | Zinc fingers, PHD-type |
Function | Chromatin remodeling |
Modification | # |
PMID for information on function | PMID:12592387 |
Protein complex | NuRD |
Target molecule | DNA |
Target entity | # |
Product | # |
PMID for information on target | PMID:12592387 |
Comment | These proteins have a DNA-binding domain as well as a chromodomain motif that can directly effect chromatin structure and gene transcription. There are currently four known members of this gene family in humans (CHD1–CHD4). |
Status of entry | # |
Expression range: | 19.52 to 476.97 |
Mean expression: | 78.02 ± 45.11 |
Median expression: | 67.66 |