HGNC approved symbol | CIT |
HGNC ID | HGNC:1985 |
HGNC approved name | citron rho-interacting serine/threonine kinase |
Entrez gene ID | GeneID:11113 (SSTAR profile) |
UniProt AC (human) | O14578 |
UniProt ID (human) | CTRO_HUMAN |
Pfam domains | Pkinase PF00069 (97-360) Pkinase_C PF00433 (376-422) PH PF00169 (1445-1563) CNH PF00780 (1602-1855) |
MGI symbol | Cit |
MGI ID | MGI:105313 |
UniProt AC (mouse) | P49025 |
UniProt ID (mouse) | CTRO_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Histone modification write cofactor, Histone modification write cofactor |
Modification | Histone methylation, Histone phosphorylation |
PMID for information on function | PMID:18245345 |
Protein complex | # |
Target molecule | histone |
Target entity | H3K9 |
Product | H3K9me |
PMID for information on target | PMID:18245345 |
Comment | Drosophila sticky/citron kinase (=CIT) is a regulator of cell-cycle progression, genetically interacts with Argonaute 1 and modulates epigenetic gene silencing. |
Status of entry | # |
Expression range: | 0.0 to 156.05 |
Mean expression: | 9.88 ± 17.13 |
Median expression: | 5.49 |