HGNC approved symbol | MYSM1 |
HGNC ID | HGNC:29401 |
HGNC approved name | Myb-like, SWIRM and MPN domains 1 |
Entrez gene ID | GeneID:114803 (SSTAR profile) |
UniProt AC (human) | Q5VVJ2 |
UniProt ID (human) | MYSM1_HUMAN |
Pfam domains | Myb_DNA-binding PF00249 (120-163) SWIRM PF04433 (382-461) JAB PF01398 (576-679) |
MGI symbol | Mysm1 |
MGI ID | MGI:2444584 |
UniProt AC (mouse) | Q69Z66 |
UniProt ID (mouse) | MYSM1_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Histone modification erase |
Modification | Histone ubiquitination |
PMID for information on function | PMID:17707232 |
Protein complex | # |
Target molecule | histone |
Target entity | H2Aub |
Product | H2A |
PMID for information on target | PMID:17707232 |
Comment | JAMM/MPN(+) domain-containing histone H2A deubiquitinase (2A-DUB, or KIAA1915/MYSM1) is specific for monoubiquitinated H2A (uH2A) that has permitted delineation of a strategy for specific regulatory pathways of gene activation. |
Status of entry | # |
Expression range: | 0.0 to 197.39 |
Mean expression: | 23.86 ± 16.08 |
Median expression: | 21.05 |