| HGNC approved symbol | CTCFL |
| HGNC ID | HGNC:16234 |
| HGNC approved name | CCCTC-binding factor (zinc finger protein)-like |
| Entrez gene ID | GeneID:140690
(SSTAR profile) |
| UniProt AC (human) | Q8NI51 |
| UniProt ID (human) | CTCFL_HUMAN |
| Pfam domains | zf-C2H2 PF00096 (313-336, 342-364, 398-421, 428-451, 546-566) |
| MGI symbol | Ctcfl |
| MGI ID | MGI:3652571 |
| UniProt AC (mouse) | A2APF3 |
| UniProt ID (mouse) | CTCFL_MOUSE |
| HGNC gene family tag | ZNF |
| HGNC gene family description | Zinc fingers, C2H2-type |
| Function | Chromatin remodeling |
| Modification | # |
| PMID for information on function | PMID:18765639 |
| Protein complex | # |
| Target molecule | DNA |
| Target entity | # |
| Product | # |
| PMID for information on target | PMID:18765639 |
| Comment | BORIS=CTCFL acts as a scaffold upon which BAT3 and SET1A assemble and through which BAT3 and SET1A exert their effects upon chromatin structure and gene expression. In contrast to CTCF, BORIS appears to be a methylation-independent DNA-binding protein (28b) that activates, rather than inhibits, gene expression. |
| Status of entry | # |