HGNC approved symbol | DTX3L |
HGNC ID | HGNC:30323 |
HGNC approved name | deltex 3 like, E3 ubiquitin ligase |
Entrez gene ID | GeneID:151636 (SSTAR profile) |
UniProt AC (human) | Q8TDB6 |
UniProt ID (human) | DTX3L_HUMAN |
Pfam domains | DTX3L_a-b PF21717 (134-194) DTX3L_KH-like PF21718 (235-357, 373-508) zf-C3HC4_2 PF13923 (561-599) DTC PF18102 (608-739) |
MGI symbol | Dtx3l |
MGI ID | MGI:2656973 |
UniProt AC (mouse) | Q3UIR3 |
UniProt ID (mouse) | DTX3L_MOUSE |
HGNC gene family tag | RNF |
HGNC gene family description | RING-type (C3HC4) zinc fingers |
Function | Histone modification write |
Modification | Histone ubiquitination |
PMID for information on function | PMID:19818714 |
Protein complex | # |
Target molecule | histone |
Target entity | H4K91 |
Product | # |
PMID for information on target | PMID:19818714 |
Comment | BBAP=DTX3L selectively monoubiquitylates histone H4 lysine 91 and protects cells exposed to DNA-damaging agents. |
Status of entry | # |
Expression range: | 0.0 to 471.36 |
Mean expression: | 32.67 ± 48.1 |
Median expression: | 20.47 |