| HGNC approved symbol | ASXL1 |
| HGNC ID | HGNC:18318 |
| HGNC approved name | additional sex combs like transcriptional regulator 1 |
| Entrez gene ID | GeneID:171023 (SSTAR profile) |
| UniProt AC (human) | Q8IXJ9 |
| UniProt ID (human) | ASXL1_HUMAN |
| Pfam domains | HARE-HTH PF05066 (11-82) ASXH PF13919 (244-363) PHD_3 PF13922 (1502-1539) |
| MGI symbol | Asxl1 |
| MGI ID | MGI:2684063 |
| UniProt AC (mouse) | P59598 |
| UniProt ID (mouse) | ASXL1_MOUSE |
| HGNC gene family tag | # |
| HGNC gene family description | # |
| Function | Histone modification erase, Polycomb group (PcG) protein |
| Modification | Histone deubiquitination |
| PMID for information on function | PMID:20436459 |
| Protein complex | PR-DUB |
| Target molecule | histone |
| Target entity | H2AK119 |
| Product | H2AK119ub1 |
| PMID for information on target | PMID:20436459 |
| Comment | Reconstituted recombinant Drosophila and human PR-DUB=ASXL1 complexes remove monoubiquitin from H2A but not from H2B in nucleosomes. |
| Status of entry | # |
| Expression range: | 7.88 to 205.67 |
| Mean expression: | 56.12 ± 29.73 |
| Median expression: | 50.08 |