HGNC approved symbol | DNMT3A |
HGNC ID | HGNC:2978 |
HGNC approved name | DNA (cytosine-5-)-methyltransferase 3 alpha |
Entrez gene ID | GeneID:1788 (SSTAR profile) |
UniProt AC (human) | Q9Y6K1 |
UniProt ID (human) | DNM3A_HUMAN |
Pfam domains | domain PF22855 (1-283) PWWP PF00855 (293-374) ADD_DNMT3 PF17980 (476-530) ADDz_Dnmt3b PF21255 (537-586) DNA_methylase PF00145 (634-766) |
MGI symbol | Dnmt3a |
MGI ID | MGI:1261827 |
UniProt AC (mouse) | O88508 |
UniProt ID (mouse) | DNM3A_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | DNA modification |
Modification | DNA methylation |
PMID for information on function | PMID:12138111 |
Protein complex | # |
Target molecule | DNA |
Target entity | dhC |
Product | dhU |
PMID for information on target | PMID:12138111 |
Comment | One form of Dnmt3a has been identified and shown to be capable of methylating DNA bothin vitro and in vivo. |
Status of entry | # |
Expression range: | 0.0 to 85.67 |
Mean expression: | 8.37 ± 10.72 |
Median expression: | 4.57 |