HGNC approved symbol | ZBTB7C |
HGNC ID | HGNC:31700 |
HGNC approved name | zinc finger and BTB domain containing 7C |
Entrez gene ID | GeneID:201501 (SSTAR profile) |
UniProt AC (human) | A1YPR0 |
UniProt ID (human) | ZBT7C_HUMAN |
Pfam domains | BTB PF00651 (24-128) zf-C2H2 PF00096 (392-414, 448-469) |
MGI symbol | Zbtb7c |
MGI ID | MGI:2443302 |
UniProt AC (mouse) | Q8VCZ7 |
UniProt ID (mouse) | ZBT7C_MOUSE |
HGNC gene family tag | ZBTB, ZNF, BTBD |
HGNC gene family description | Zinc fingers, C2H2-type, BTB/POZ domain containing |
Function | Histone modification cofactor |
Modification | # |
PMID for information on function | PMID:21804610 |
Protein complex | # |
Target molecule | histone |
Target entity | # |
Product | # |
PMID for information on target | PMID:21804610 |
Comment | Kr-pok =ZBTB7C competes with MIZ-1 in binding to these elements and represses transcription by inhibiting MIZ-1/p300 recruitment, which decreases the acetylation of histones H3 and H4. |
Status of entry | # |
Expression range: | 0.0 to 59.55 |
Mean expression: | 2.03 ± 5.61 |
Median expression: | 0.0 |