HGNC approved symbol | KDM4B |
HGNC ID | HGNC:29136 |
HGNC approved name | lysine (K)-specific demethylase 4B |
Entrez gene ID | GeneID:23030 (SSTAR profile) |
UniProt AC (human) | O94953 |
UniProt ID (human) | KDM4B_HUMAN |
Pfam domains | JmjN PF02375 (16-50) JmjC PF02373 (176-292) PHD_2 PF13831 (754-789) zf-HC5HC2H_2 PF13832 (796-907) Tudor_2 PF18104 (922-956, 978-1014) |
MGI symbol | Kdm4b |
MGI ID | MGI:2442355 |
UniProt AC (mouse) | Q91VY5 |
UniProt ID (mouse) | KDM4B_MOUSE |
HGNC gene family tag | KDM, TDRD |
HGNC gene family description | Chromatin-modifying enzymes / K-demethylases, Tudor domain containing |
Function | Histone modification erase |
Modification | Histone methylation |
PMID for information on function | PMID:16603238 |
Protein complex | # |
Target molecule | histone |
Target entity | H3K9me3 |
Product | H3K9me1, H3K9me2 |
PMID for information on target | PMID:16603238 |
Comment | Human JMJD2(B, C, D) =KDM4(B, C, D) subfamily members function as trimethylation-specific demethylases, converting H3-K9Me3 to H3-K9Me2 and H3-K9Me1, respectively. |
Status of entry | # |
Expression range: | 4.48 to 345.21 |
Mean expression: | 38.29 ± 28.18 |
Median expression: | 33.75 |