| HGNC approved symbol | PHF8 |
| HGNC ID | HGNC:20672 |
| HGNC approved name | PHD finger protein 8 |
| Entrez gene ID | GeneID:23133 (SSTAR profile) |
| UniProt AC (human) | Q9UPP1 |
| UniProt ID (human) | PHF8_HUMAN |
| Pfam domains | PHD PF00628 (44-89) JmjC PF02373 (270-370) JHD PF17811 (374-481) |
| MGI symbol | Phf8 |
| MGI ID | MGI:2444341 |
| UniProt AC (mouse) | Q80TJ7 |
| UniProt ID (mouse) | PHF8_MOUSE |
| HGNC gene family tag | KDM, PHF |
| HGNC gene family description | Chromatin-modifying enzymes / K-demethylases, Zinc fingers, PHD-type |
| Function | Histone modification erase |
| Modification | Histone methylation |
| PMID for information on function | PMID:21423274 |
| Protein complex | # |
| Target molecule | histone |
| Target entity | H3K9me1, H3K9me2, H3K27me2, H4K20me1, H3K36me2, H3K36me3, H3K4me3 |
| Product | H3K9, H3K27, H4K20, H3K36, H3K4 |
| PMID for information on target | PMID:21423274 |
| Comment | Table 1 in the reference. Via its PWWP domain it specifically binds trimethylated 'Lys-36' of histone H3 (H3K36me3): early recruitment to chromatin to be replicated allowing a quick identification of mismatch repair to initiate the DNA mismatch repair rea |
| Status of entry | # |
| Expression range: | 0.0 to 59.92 |
| Mean expression: | 12.5 ± 7.38 |
| Median expression: | 10.96 |