HGNC approved symbol | JADE2 |
HGNC ID | HGNC:22984 |
HGNC approved name | jade family PHD finger 2 |
Entrez gene ID | GeneID:23338 (SSTAR profile) |
UniProt AC (human) | Q9NQC1 |
UniProt ID (human) | JADE2_HUMAN |
Pfam domains | EPL1 PF10513 (16-177) PHD_2 PF13831 (214-247) zf-HC5HC2H_2 PF13832 (253-364) |
MGI symbol | Jade2 |
MGI ID | MGI:1924151 |
UniProt AC (mouse) | Q6ZQF7 |
UniProt ID (mouse) | JADE2_MOUSE |
HGNC gene family tag | PHF |
HGNC gene family description | Zinc fingers, PHD-type |
Function | Histone modification write |
Modification | Histone acetylation |
PMID for information on function | PMID:16387653 |
Protein complex | HBO1 |
Target molecule | histone |
Target entity | H3, H4 |
Product | H3ac, H4ac |
PMID for information on target | PMID:16387653 |
Comment | HBO1-JADE(1,2,3=PHF15,PHF16,PHF17)-ING-hEAF6 tetramer complexes are likely responsible for the majority of histone H4 acetylation higher eukaryotes. |
Status of entry | # |
Expression range: | 0.0 to 151.51 |
Mean expression: | 14.09 ± 12.59 |
Median expression: | 10.06 |