| HGNC approved symbol | RYBP |
| HGNC ID | HGNC:10480 |
| HGNC approved name | RING1 and YY1 binding protein |
| Entrez gene ID | GeneID:23429 (SSTAR profile) |
| UniProt AC (human) | Q8N488 |
| UniProt ID (human) | RYBP_HUMAN |
| Pfam domains | zf-RanBP PF00641 (22-45) YAF2_RYBP PF17219 (146-178) |
| MGI symbol | Rybp |
| MGI ID | MGI:1929059 |
| UniProt AC (mouse) | Q8CCI5 |
| UniProt ID (mouse) | RYBP_MOUSE |
| HGNC gene family tag | # |
| HGNC gene family description | # |
| Function | Polycomb group (PcG) protein |
| Modification | # |
| PMID for information on function | PMID:19098711 |
| Protein complex | BCOR, RING2-L3MBTL2, RING2-FBRS |
| Target molecule | # |
| Target entity | # |
| Product | # |
| PMID for information on target | PMID:19098711 |
| Comment | RYBP (RING1- and YY1-binding protein), a member of the polycomb group (PcG), interacts with MDM2 and decreases MDM2-mediated p53 ubiquitination, leading to stabilization of p53 and an increase in p53 activity. |
| Status of entry | # |
| Expression range: | 0.0 to 75.74 |
| Mean expression: | 4.57 ± 4.81 |
| Median expression: | 3.44 |