HGNC approved symbol | SIN3A |
HGNC ID | HGNC:19353 |
HGNC approved name | SIN3 transcription regulator family member A |
Entrez gene ID | GeneID:25942 (SSTAR profile) |
UniProt AC (human) | Q96ST3 |
UniProt ID (human) | SIN3A_HUMAN |
Pfam domains | PAH PF02671 (142-186, 323-380, 478-522) Sin3_corepress PF08295 (551-647) Sin3a_C PF16879 (885-1192) |
MGI symbol | Sin3a |
MGI ID | MGI:107157 |
UniProt AC (mouse) | Q60520 |
UniProt ID (mouse) | SIN3A_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Histone modification erase cofactor, TF |
Modification | Histone acetylation, TF activator, TF repressor |
PMID for information on function | PMID:12670868 |
Protein complex | SWI/SNF_Brg1(I), SWI/SNF_Brm, mSin3A, mSin3A-like complex |
Target molecule | histone, DNA |
Target entity | DNA motif |
HOCOMOCO TFBS model | |
Product | # |
PMID for information on target | PMID:12670868 |
Comment | Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1. |
Status of entry | # |
Expression range: | 1.74 to 195.09 |
Mean expression: | 27.5 ± 18.6 |
Median expression: | 23.2 |