HGNC approved symbol | KAT2A |
HGNC ID | HGNC:4201 |
HGNC approved name | K(lysine) acetyltransferase 2A |
Entrez gene ID | GeneID:2648 (SSTAR profile) |
UniProt AC (human) | Q92830 |
UniProt ID (human) | KAT2A_HUMAN |
Pfam domains | PCAF_N PF06466 (92-335) Acetyltransf_1 PF00583 (536-627) Bromodomain PF00439 (738-819) |
MGI symbol | Kat2a |
MGI ID | MGI:1343101 |
UniProt AC (mouse) | Q9JHD2 |
UniProt ID (mouse) | KAT2A_MOUSE |
HGNC gene family tag | KAT |
HGNC gene family description | Chromatin-modifying enzymes / K-acetyltransferases |
Function | Histone modification write |
Modification | Histone acetylation |
PMID for information on function | PMID:10611234 |
Protein complex | TFTC-HAT, SAGA, ATAC, STAGA |
Target molecule | histone |
Target entity | # |
Product | # |
PMID for information on target | PMID:10611234 |
Comment | Current models of HAT protein activity suggest that one hypothesis for the role of hGCN5=KAT2A in c-Myc's activities might be due to the relaxing of chromatin packaging at target genes following histone acetylation by hGCN5. |
Status of entry | # |
Expression range: | 0.0 to 130.42 |
Mean expression: | 19.74 ± 14.14 |
Median expression: | 15.96 |