HGNC approved symbol | SETD2 |
HGNC ID | HGNC:18420 |
HGNC approved name | SET domain containing 2 |
Entrez gene ID | GeneID:29072 (SSTAR profile) |
UniProt AC (human) | Q9BYW2 |
UniProt ID (human) | SETD2_HUMAN |
Pfam domains | AWS PF17907 (1513-1547) SET PF00856 (1561-1667) WW PF00397 (2391-2421) SRI PF08236 (2471-2552) |
MGI symbol | Setd2 |
MGI ID | MGI:1918177 |
UniProt AC (mouse) | E9Q5F9 |
UniProt ID (mouse) | SETD2_MOUSE |
HGNC gene family tag | KMT |
HGNC gene family description | Chromatin-modifying enzymes / K-methyltransferases |
Function | Histone modification write |
Modification | Histone methylation |
PMID for information on function | PMID:16118227 |
Protein complex | # |
Target molecule | histone |
Target entity | H3K36me2 |
Product | H3K36me3 |
PMID for information on target | PMID:16118227 |
Comment | HYPB HMTase=SETD2 may coordinate histone methylation and transcriptional regulation in mammals. |
Status of entry | # |
Expression range: | 0.0 to 157.13 |
Mean expression: | 15.61 ± 11.56 |
Median expression: | 12.92 |