HGNC approved symbol | HMGB1 |
HGNC ID | HGNC:4983 |
HGNC approved name | high mobility group box 1 |
Entrez gene ID | GeneID:3146 (SSTAR profile) |
UniProt AC (human) | P09429 |
UniProt ID (human) | HMGB1_HUMAN |
Pfam domains | HMG_box_2 PF09011 (6-79) HMG_box PF00505 (95-163) |
MGI symbol | Hmgb1 |
MGI ID | MGI:96113 |
UniProt AC (mouse) | P63158 |
UniProt ID (mouse) | HMGB1_MOUSE |
HGNC gene family tag | HMG |
HGNC gene family description | High-mobility group / Canonical |
Function | Chromatin remodeling |
Modification | # |
PMID for information on function | PMID:19158276 |
Protein complex | # |
Target molecule | chromatin |
Target entity | # |
Product | # |
PMID for information on target | # |
Comment | Chromatin-specific remodeling by HMGB1 and linker histone H1 silences proinflammatory genes during endotoxin tolerance. |
Status of entry | # |
Expression range: | 7.4 to 401.57 |
Mean expression: | 99.37 ± 58.59 |
Median expression: | 87.72 |