| HGNC approved symbol | JARID2 |
| HGNC ID | HGNC:6196 |
| HGNC approved name | jumonji, AT rich interactive domain 2 |
| Entrez gene ID | GeneID:3720 (SSTAR profile) |
| UniProt AC (human) | Q92833 |
| UniProt ID (human) | JARD2_HUMAN |
| Pfam domains | JmjN PF02375 (558-591) ARID PF01388 (624-709) JmjC PF02373 (916-1031) zf-C5HC2 PF02928 (1139-1191) |
| MGI symbol | Jarid2 |
| MGI ID | MGI:104813 |
| UniProt AC (mouse) | Q62315 |
| UniProt ID (mouse) | JARD2_MOUSE |
| HGNC gene family tag | # |
| HGNC gene family description | # |
| Function | Histone modification write cofactor |
| Modification | Histone methylation |
| PMID for information on function | PMID:20075857 |
| Protein complex | PRC2 |
| Target molecule | histone |
| Target entity | H3K27, H3K9 |
| Product | # |
| PMID for information on target | PMID:20075857 |
| Comment | JARID2 is sufficient to recruit PcG proteins to a heterologous promoter, and inhibition of JARID2 expression leads to a major loss of PcG binding and to a reduction of H3K27me3 levels on target genes. |
| Status of entry | # |
| Expression range: | 0.0 to 1344.48 |
| Mean expression: | 62.37 ± 106.87 |
| Median expression: | 28.38 |