HGNC approved symbol | GADD45B |
HGNC ID | HGNC:4096 |
HGNC approved name | growth arrest and DNA-damage-inducible, beta |
Entrez gene ID | GeneID:4616 (SSTAR profile) |
UniProt AC (human) | O75293 |
UniProt ID (human) | GA45B_HUMAN |
Pfam domains | Ribosomal_L7Ae PF01248 (22-116) |
MGI symbol | Gadd45b |
MGI ID | MGI:107776 |
UniProt AC (mouse) | P22339 |
UniProt ID (mouse) | GA45B_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Chromatin remodeling |
Modification | # |
PMID for information on function | PMID:21986581 |
Protein complex | # |
Target molecule | histone |
Target entity | H2A, H2B, H3, H4 |
Product | # |
PMID for information on target | PMID:21986581 |
Comment | Active DNA demethylation is partially attributed to the ability of Gadd45(A, B, C) proteins to bind histones and modify accessibility of DNA on damaged chromatin. |
Status of entry | # |