HGNC approved symbol | PHF1 |
HGNC ID | HGNC:8919 |
HGNC approved name | PHD finger protein 1 |
Entrez gene ID | GeneID:5252 (SSTAR profile) |
UniProt AC (human) | O43189 |
UniProt ID (human) | PHF1_HUMAN |
Pfam domains | Tudor_2 PF18104 (34-69) PHD PF00628 (90-139) Mtf2_C PF14061 (534-564) |
MGI symbol | Phf1 |
MGI ID | MGI:98647 |
UniProt AC (mouse) | Q9Z1B8 |
UniProt ID (mouse) | PHF1_MOUSE |
HGNC gene family tag | TDRD, PHF |
HGNC gene family description | Tudor domain containing, Zinc fingers, PHD-type |
Function | Polycomb group (PcG) protein |
Modification | # |
PMID for information on function | PMID:18086877 |
Protein complex | PRC2 |
Target molecule | # |
Target entity | # |
Product | # |
PMID for information on target | PMID:18086877 |
Comment | The EED-EZH2 complex, containing the core subunits EZH2, EED, SUZ12, and RbAp48, functions as a histone H3K27-specific methyltransferase. The related EED-EZH2 protein complex is distinguished from the previous complex by the presence of another PcG protein, hPHF1. |
Status of entry | # |
Expression range: | 3.22 to 378.21 |
Mean expression: | 28.18 ± 30.5 |
Median expression: | 20.59 |