HGNC approved symbol | PPP2CA |
HGNC ID | HGNC:9299 |
HGNC approved name | protein phosphatase 2, catalytic subunit, alpha isozyme |
Entrez gene ID | GeneID:5515 (SSTAR profile) |
UniProt AC (human) | P67775 |
UniProt ID (human) | PP2AA_HUMAN |
Pfam domains | Metallophos PF00149 (51-244) |
MGI symbol | Ppp2ca |
MGI ID | MGI:1321159 |
UniProt AC (mouse) | P63330 |
UniProt ID (mouse) | PP2AA_MOUSE |
HGNC gene family tag | PPP |
HGNC gene family description | Serine/threonine phosphatases / Protein phosphatase, catalytic subunits |
Function | Histone modification write |
Modification | Histone phosphorylation |
PMID for information on function | PMID:18758438 |
Protein complex | # |
Target molecule | histone |
Target entity | H2AX |
Product | H2AXph |
PMID for information on target | PMID:18758438 |
Comment | PP2A =PPP2CA (rather than PP4) has been implicated as a mammalian γH2AX phosphatase. |
Status of entry | # |