| HGNC approved symbol | ASXL2 |
| HGNC ID | HGNC:23805 |
| HGNC approved name | additional sex combs like transcriptional regulator 2 |
| Entrez gene ID | GeneID:55252 (SSTAR profile) |
| UniProt AC (human) | Q76L83 |
| UniProt ID (human) | ASXL2_HUMAN |
| Pfam domains | HARE-HTH PF05066 (11-84) ASXH PF13919 (266-381) PHD_3 PF13922 (1376-1433) |
| MGI symbol | Asxl2 |
| MGI ID | MGI:1922552 |
| UniProt AC (mouse) | Q8BZ32 |
| UniProt ID (mouse) | ASXL2_MOUSE |
| HGNC gene family tag | # |
| HGNC gene family description | # |
| Function | Histone modification read |
| Modification | # |
| PMID for information on function | PMID:21047783 |
| Protein complex | # |
| Target molecule | histone |
| Target entity | H3K4, H3K9 |
| Product | # |
| PMID for information on target | PMID:21047783 |
| Comment | ASXL2 occupies the aP2 promoter together with histone-lysine N-methyltransferase MLL1 and Lys-9-acetylated and Lys-4-methylated H3 histones. Microarray analysis demonstrated that ASXL1 represses, whereas ASXL2 increases, the expression of adipogenic genes. |
| Status of entry | # |
| Expression range: | 1.48 to 126.08 |
| Mean expression: | 24.67 ± 13.15 |
| Median expression: | 22.54 |