HGNC approved symbol | HJURP |
HGNC ID | HGNC:25444 |
HGNC approved name | Holliday junction recognition protein |
Entrez gene ID | GeneID:55355 (SSTAR profile) |
UniProt AC (human) | Q8NCD3 |
UniProt ID (human) | HJURP_HUMAN |
Pfam domains | Scm3 PF10384 (11-71) HJURP_mid PF12346 (123-391) HJURP_C PF12347 (416-466, 560-620) |
MGI symbol | Hjurp |
MGI ID | MGI:2685821 |
UniProt AC (mouse) | Q6PG16 |
UniProt ID (mouse) | HJURP_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Histone chaperone |
Modification | # |
PMID for information on function | PMID:21478274 |
Protein complex | # |
Target molecule | histone |
Target entity | H4 |
Product | # |
PMID for information on target | PMID:21478274 |
Comment | Deposition of CENP-A to the centromere requires histone chaperone HJURP (Holliday junction recognition protein). The crystal structure of an HJURP–CENP-A–histone H4 complex shows that HJURP binds a CENP-A–H4 heterodimer. |
Status of entry | # |
Expression range: | 0.0 to 212.55 |
Mean expression: | 20.81 ± 25.45 |
Median expression: | 11.82 |