| HGNC approved symbol | SMEK1 |
| HGNC ID | HGNC:20219 |
| HGNC approved name | SMEK homolog 1, suppressor of mek1 (Dictyostelium) |
| Entrez gene ID | GeneID:55671 (SSTAR profile) |
| UniProt AC (human) | Q6IN85 |
| UniProt ID (human) | P4R3A_HUMAN |
| Pfam domains | domain PF22972 (5-101) PP4R3 PF04802 (141-645) |
| MGI symbol | Smek1 |
| MGI ID | MGI:1915984 |
| UniProt AC (mouse) | Q6P2K6 |
| UniProt ID (mouse) | P4R3A_MOUSE |
| HGNC gene family tag | # |
| HGNC gene family description | # |
| Function | Histone modification erase cofactor |
| Modification | Histone phosphorylation |
| PMID for information on function | PMID:18614045 |
| Protein complex | PPP4C-PPP4R2-PPP4R3A |
| Target molecule | histone |
| Target entity | H2AFX |
| Product | # |
| PMID for information on target | # |
| Comment | Member of PPP4C-PPP4R2-PPP4R3A PP4 complex which specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX). |
| Status of entry | # |
| Expression range: | 5.32 to 173.89 |
| Mean expression: | 39.45 ± 26.12 |
| Median expression: | 32.41 |